# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5034094 | B | Inhibition of recombinant GST-tagged N-terminal truncated human Aurora A (123 to 401 residues) expressed in Sf9 insect cell using tetra-LRRASLG peptide as substrate incubated for 20 mins by Kinase-Glo plus luminescent kinase assay | Homo sapiens | 24 | ALA5033992 | cell-based format | Scientific Literature | |
2. | ALA5034096 | F | Effect on cMYC protein expression level in human NCI-H82 cells assessed as fold change at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 17 | ALA5033992 | cell-based format | Scientific Literature | |
3. | ALA5034097 | F | Effect on MYCN protein expression level in human SKNBE2 cells assessed as fold change at 1 uM incubated for 24 hrs by Western blot analysis relative to control | Homo sapiens | 17 | ALA5033992 | cell-based format | Scientific Literature | |
4. | ALA5034098 | B | Inhibition of Aurora A phosphorylation in human NCI-H82 cells assessed as reduction in phosphorylation at Thr 288 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
5. | ALA5034099 | B | Inhibition of Aurora B phosphorylation in human NCI-H82 cells assessed as reduction in phosphorylation at Thr 232 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
6. | ALA5034100 | B | Inhibition of Histone H3 phosphorylation in human NCI-H82 cells assessed as reduction in phosphorylation at Ser 10 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
7. | ALA5034101 | B | Inhibition of Aurora A phosphorylation in human SKNBE2 cells assessed as reduction in phosphorylation at Thr 288 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
8. | ALA5034102 | B | Inhibition of Aurora B phosphorylation in human SKNBE2 cells assessed as reduction in phosphorylation at Thr 232 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
9. | ALA5034103 | B | Inhibition of Histone H3 phosphorylation in human SKNBE2cells assessed as reduction in phosphorylation at Ser 10 residue at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | tissue-based format | Scientific Literature | |
10. | ALA5034104 | F | Down regulation of Cyclin B1 expression in human NCI-H82 cells at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
11. | ALA5034105 | F | Down regulation of Cyclin B1 expression in human SKNBE2 cells at 50 to 1000 nM after 24 hrs by Western blot analysis | Homo sapiens | 2 | ALA5033992 | cell-based format | Scientific Literature | |
12. | ALA5034106 | F | Growth inhibition of human NCI-H82 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 3 | ALA5033992 | cell-based format | Scientific Literature | |
13. | ALA5034107 | F | Growth inhibition of human NCI-H211 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
14. | ALA5034108 | F | Growth inhibition of human NCI-H446 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
15. | ALA5034109 | F | Growth inhibition of human NCI-H524 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
16. | ALA5034110 | F | Growth inhibition of human NCI-H2171 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
17. | ALA5034111 | F | Growth inhibition of human NCI-H526 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
18. | ALA5034112 | F | Growth inhibition of human NCI-H209 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
19. | ALA5034113 | F | Growth inhibition of human NCI-H146 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | cell-based format | Scientific Literature | |
20. | ALA5034114 | F | Growth inhibition of human NCI-H841 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay | Homo sapiens | 1 | ALA5033992 | tissue-based format | Scientific Literature |