# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053070 | F | Antiproliferative activity against doxycycline-induced NGLY1 knocked down human UACC-257 cells at 20 uM in presence of dacarbazine assessed as decrease in growth inhibition after 72 hrs by MTT assay | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
2. | ALA5053071 | F | Antiproliferative activity against doxycycline-induced NGLY1 knocked down human Malme-3M cells at 20 uM in presence of dacarbazine assessed as decrease in growth inhibition after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
3. | ALA5053072 | B | Inhibition of NGLY1 in human HEK293T cells at 200 uM assessed as retention of N-glycans on full-length NFE2L1 measured by electrophoretic mobility shift assay | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data | ||
4. | ALA5053073 | F | Antiproliferative activity against human UACC-257 cells at 10 to 1000 uM assessed as decrease in cell viability | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
5. | ALA5053074 | F | Antiproliferative activity against human SK-MEL-2 cells at 10 to 1000 uM assessed as decrease in cell viability | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
6. | ALA5053075 | T | Antiproliferative activity against human HDF51 cells at 10 to 1000 uM assessed as decrease in cell viability | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
7. | ALA5053076 | T | Antiproliferative activity against human HDF418 cells at 10 to 1000 uM assessed as decrease in cell viability | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
8. | ALA5053077 | B | Inhibition of NGLY1 in human UACC-257 cells at 200 uM assessed as increase in IFN-beta1 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
9. | ALA5053078 | B | Inhibition of NGLY1 in human UACC-257 cells at 200 uM assessed as increase in IL-29 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
10. | ALA5053079 | B | Inhibition of NGLY1 in human SK-MEL-2 cells at 200 uM assessed as increase in IFN-beta1 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
11. | ALA5053080 | B | Inhibition of NGLY1 in human SK-MEL-2 cells at 200 uM assessed as increase in IL-29 production measured after 48 hrs | Homo sapiens | 3 | cell-based format | Patent Bioactivity Data | ||
12. | ALA5053084 | F | Antiproliferative activity against human SK-MEL-2 cells assessed as decrease in cell viability in presence of bortezomib | Homo sapiens | 1 | cell-based format | Patent Bioactivity Data |