# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5041681 | T | Cytotoxicity against human Huh7.5 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA5041682 | F | Antiviral activity against HCV infected in human Huh7.5 cells incubated for 72 hrs by in-cell western assay | Hepacivirus hominis | 33 | organism-based format | Scientific Literature | ||
3. | ALA5041683 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh7.5.1 cells to EC50 for antiviral activity against HCV infected in human Huh7.5.1 cells | 27 | cell-based format | Scientific Literature | |||
4. | ALA5041695 | F | Antagonist activity against H1 receptor (unknown origin) expressed in HEK cells at 1 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
5. | ALA5041696 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in viral RNA level preincubated for 2 hrs prior to viral infection and measured after 72 hrs by RT-qPCR analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
6. | ALA5041697 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in viral RNA level measured after 72 hrs by RT-qPCR analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
7. | ALA5041698 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in HCV core protein expression measured after 72 hrs by Western blotting analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
8. | ALA5041699 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in HCV core protein expression preincubated for 2 hrs followed by viral infection and measured after 72 hrs by Western blotting analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
9. | ALA5041700 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in HCV core protein expression pre-infected with virus for 2 hrs followed by compound addition and measured after 72 hrs by Western blotting analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
10. | ALA5041701 | F | Antiviral activity against HCV infected in human Huh7.5 cells carrying HCV subgenomic replicons assessed as inhibition of viral replication at 1.4 uM | Hepacivirus hominis | 3 | organism-based format | Scientific Literature | ||
11. | ALA5041702 | T | Selectivity index, ratio of CC50 for cytotoxicity against human Huh7.5 cells infected with HCVcc to EC50 for antiviral activity against HCVcc infected in human Huh7.5 cells | 6 | cell-based format | Scientific Literature | |||
12. | ALA5041703 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in HCV core protein expression at 6.4 nM incubated for 72 hrs by in-cell western assay | Hepacivirus hominis | 6 | organism-based format | Scientific Literature | ||
13. | ALA5041704 | F | Antiviral activity against HCV infected in human Huh7.5 cells assessed as reduction in viral RNA level pre-infected with virus for 2 hrs followed by compound addition and measured after 72 hrs by RT-qPCR analysis | Hepacivirus hominis | 3 | organism-based format | Scientific Literature |