#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5040041	A	Metabolic stability in mouse liver microsomes assessed as half life at 5 uM	Mus musculus	31		microsome format	Scientific Literature
2.	ALA5040044	P	Kinetic aqueous solubility of compound in PBS at pH 7.4 at 250 uM		32		small-molecule physicochemical format	Scientific Literature
3.	ALA5040045	B	Inhibition of NKCC1 in mouse primary hippocampal neurons assessed as reduction of Ca2+ uptake at 10 uM incubated for 15 mins by Fluo-4AM dye based fluorescence analysis relative to control	Mus musculus	14		cell-based format	Scientific Literature
4.	ALA5040046	B	Inhibition of NKCC1 in mouse primary hippocampal neurons assessed as reduction of Ca2+ uptake at 100 uM incubated for 15 mins by Fluo-4AM dye based fluorescence analysis relative to control	Mus musculus	10		cell-based format	Scientific Literature
5.	ALA5040047	A	Stability in mouse plasma assessed as half life at 5 uM	Mus musculus	13		cell-free format	Scientific Literature
6.	ALA5040048	B	Inhibition of KCC2 (unknown origin) transfected in HEK293 cells assessed a reduction in TI influx at 10 uM incubated for 1 hr by fluorescence based analysis relative to control	Homo sapiens	1		cell-based format	Scientific Literature
7.	ALA5040049	B	Inhibition of NKCC1 (unknown origin) transfected in HEK293 cells expressing mbYFPQS plasmid assessed as reduction in Cl- influx at 10 uM incubated for 30 mins by fluorescence multiplate reader analysis	Homo sapiens	22		cell-based format	Scientific Literature
8.	ALA5040050	F	Diuretic activity in wild type mouse assessed as increase in urine volume at 0.6 mg/kg, ip measured after 2 hrs	Mus musculus	2		organism-based format	Scientific Literature
9.	ALA5040051	F	Diuretic activity in Ts65Dn mouse assessed as increase in urine volume at 0.6 mg/kg, ip measured after 2 hrs	Mus musculus	2		organism-based format	Scientific Literature
10.	ALA5040052	F	Cognitive enhancement effect in Ts65Dn mouse assessed as restoration of short-term working memory by measuring number of correct choices at 0.6 mg/kg, ip measured after 1 to 4 weeks by T-maze test	Mus musculus	1		organism-based format	Scientific Literature
11.	ALA5040053	F	Cognitive enhancement effect in Ts65Dn mouse assessed as rescue of poor novel-discrimination ability by measuring increase in time spent in exploring novel object at 0.6 mg/kg, ip measured after 1 to 4 weeks by novel object recognition test	Mus musculus	1		organism-based format	Scientific Literature
12.	ALA5040054	F	Cognitive enhancement effect in Ts65Dn mouse assessed as rescue of electric shock induced freezing response at 0.6 mg/kg, ip measured after 1 to 4 weeks by contextual fear-conditioning test	Mus musculus	1		organism-based format	Scientific Literature
13.	ALA5040055	T	Toxicity in mouse assessed as reduction in body weight at 0.6 mg/kg, ip administered daily for 3 weeks	Mus musculus	1		organism-based format	Scientific Literature
14.	ALA5040058	F	Rescue of hyperactivity in Ts65Dn mouse assessed as assessed as reduction in total distance travelled at 0.6 mg/kg, ip measured after 1 to 4 weeks by open field test	Mus musculus	1		organism-based format	Scientific Literature
15.	ALA5040059	T	Toxicity in Ts65Dn mouse assessed as reduction in body weight at 0.6 mg/kg, ip administered daily for 3 weeks	Mus musculus	1		organism-based format	Scientific Literature