# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5056844 | B | Binding affinity to human BRD3 domain 1 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
2. | ALA5056845 | B | Binding affinity to human BRD2 domain 2 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
3. | ALA5056846 | B | Binding affinity to human BRD2 domain 1 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
4. | ALA5056847 | F | Cytotoxicity against human HL-60 cells assessed as cell viability at 5 uM by CellTiter-Glo luminescent assay | Homo sapiens | 9 | ALA5055650 | cell-based format | Scientific Literature | |
5. | ALA5056848 | F | Cytotoxicity against human TALL-1 cells assessed as cell viability at 5 uM by CellTiter-Glo luminescent assay | Homo sapiens | 9 | ALA5055650 | cell-based format | Scientific Literature | |
6. | ALA5056849 | F | Cytotoxicity against human MOLT-4 cells assessed as cell viability at 5 uM by CellTiter-Glo luminescent assay | Homo sapiens | 9 | ALA5055650 | cell-based format | Scientific Literature | |
7. | ALA5056850 | B | Binding affinity to human BRD4 domain 1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
8. | ALA5056851 | B | Inhibition of human recombinant HDAC6 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate reader | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
9. | ALA5056852 | B | Inhibition of human recombinant HDAC1 assessed as fluorescence using fluorogenic substrate ZMAL incubated for 90 min by microplate reader | Homo sapiens | 14 | ALA5055650 | single protein format | Scientific Literature | |
10. | ALA5056853 | B | Binding affinity to human BRD3 domain 2 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
11. | ALA5056854 | B | Binding affinity to human BRD7 assessed as dissociation constant by isothermal titration calorimetry assay | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
12. | ALA5056855 | B | Inhibition of human HDAC2 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nm | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
13. | ALA5056856 | B | Inhibition of human HDAC3 assessed as target activity using fluorogenic substrate ZMAL for 90 min by microplate reader at 355nm | Homo sapiens | 5 | ALA5055650 | single protein format | Scientific Literature | |
14. | ALA5056857 | F | Anticancer activity against human HPBALL cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
15. | ALA5056858 | F | Anticancer activity against human TALL-1 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
16. | ALA5056859 | F | Anticancer activity against human HL-60 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
17. | ALA5056860 | F | Anticancer activity against human K562 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
18. | ALA5056861 | F | Anticancer activity against human HAL-01 cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
19. | ALA5056862 | F | Anticancer activity against human REH cells assessed as cell growth inhibition by CellTiter-Glo luminescent assay | Homo sapiens | 6 | ALA5055650 | cell-based format | Scientific Literature | |
20. | ALA5056868 | F | Induction of apoptosis in human K562 cells assessed as apoptosis at 2.9 uM after 24 to 72 hrs using annexin V/PI followed by flow cytometry | Homo sapiens | 1 | ALA5055650 | cell-based format | Scientific Literature |