# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5057643 | F | Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins by AlphaLISA assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA5057644 | F | Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins by AlphaLISA assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA5057645 | B | Selectivity ratio of EC50 for agonist activity at human C3aR expressed in CHO cells to EC50 for agonist activity at human C5aR1 expressed in CHO cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
4. | ALA5057650 | F | Agonist activity at C5aR1 in human MDM cells assessed as induction of induction of phosphorylation of ERK1/2 at Thr202/Tyr204 residues measured after 10 mins by AlphaLISA assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA5057651 | F | Agonist activity at C5aR1 in human MDM cells assessed as induction of induction of phosphorylation of ERK1/2 at Thr202/Tyr204 residues by measuring efficacy at 4 uM pretreated with antagonist PMX53 for 30 mins followed by compound treatment for 10 mins by AlphaLISA assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA5057652 | F | Agonist activity at C5aR1 in human MDM cells assessed as induction of induction of phosphorylation of ERK1/2 at Thr202/Tyr204 residues by measuring efficacy measured after 10 mins by AlphaLISA assay relative to C5a | Homo sapiens | 2 | cell-based format | Scientific Literature |