| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5057643 | F | Agonist activity at human C3aR expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins by AlphaLISA assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 2. | ALA5057644 | F | Agonist activity at human C5aR1 expressed in CHO cells assessed as induction of ERK1/2 phosphorylation at Thr202/Tyr204 residues incubated for 10 mins by AlphaLISA assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 3. | ALA5057645 | B | Selectivity ratio of EC50 for agonist activity at human C3aR expressed in CHO cells to EC50 for agonist activity at human C5aR1 expressed in CHO cells | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 4. | ALA5057653 | A | Half life in 20% human serum at 40 uM by LC-MS analysis | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 5. | ALA5057656 | A | Stability in 100% human serum assessed as drug disappearance measured at 5 mins by LC-MS analysis | Homo sapiens | 2 | cell-free format | Scientific Literature |
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