# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053561 | Binding | Inhibition of 2-FAM-InsP5 binding to human SHIP2 catalytic domain (419 to 832 residues) assessed as change in polarization by fluorescence polarization based displacement assay | Homo sapiens | 15 | ALA5053481 | single protein format | Scientific Literature | |
2. | ALA5053562 | Binding | Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as phosphate release using Ins(1,3,4,5)P4 as substrate incubated for 20 mins measured using microplate reader | Homo sapiens | 11 | ALA5053481 | single protein format | Scientific Literature | |
3. | ALA5053563 | Binding | Inhibition of human SHIP2 catalytic domain (419 to 832 residues) phosphatase activity assessed as inhibition of Ins(1,3,4,5)P4 production using Ins(1,3,4,5)P4 as substrate incubated for 20 mins measured using microplate reader | Homo sapiens | 11 | ALA5053481 | single protein format | Scientific Literature | |
4. | ALA5053566 | Binding | Inhibition of human SHIP2 (419 to 732 residues) expressed in Escherichia coli by malachite green phosphate assay | Homo sapiens | 3 | ALA5053481 | assay format | Scientific Literature |