#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5036149	Functional	Reduction in C26:0/C16:0 LPC level in ABCD1 knock out mouse CNS at 10 mg/kg, po qd and measured after 3 months relative to control	Mus musculus	1	ALA5034039	organism-based format	Scientific Literature
2.	ALA5036150	Functional	Reduction in C26:0/C16:0 LPC level in ABCD1 knock out mouse CNS at 10 mg/kg, po qd and measured after 8 months relative to control	Mus musculus	1	ALA5034039	organism-based format	Scientific Literature
3.	ALA5132810	Binding	Inhibition of ELOVL-1 in human HEK2936E cells assessed as reduction in C24:0 lysophosphatidyl choline synthesis at 100 nM in presence of 13C-labeled acetate measured after 48 hrs	Homo sapiens	1	ALA5131397	cell-based format	Scientific Literature
4.	ALA5132811	ADME	Oral bioavailability in Sprague-Dawley rat at 3 mg/kg upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1	ALA5131397	organism-based format	Scientific Literature
5.	ALA5132812	ADME	Efflux ratio of permeability across apical to basolateral side over basolateral to apical side in dog MDCK-MDR1 transfected cells by LC-MS analysis	Canis lupus familiaris	1	ALA5131397	cell-based format	Scientific Literature
6.	ALA5132813	ADME	Unbound brain-to-plasma concentration ratio in rat at 3 mg/kg, po measured after 120 mins	Rattus norvegicus	1	ALA5131397	organism-based format	Scientific Literature
7.	ALA5132814	Functional	Cytotoxicity against human HepG2 cells assessed as decrease in intracellular ATP levels incubated for 72 hrs by Cell Titer-Glo luminescence assay	Homo sapiens	1	ALA5131397	cell-based format	Scientific Literature
8.	ALA5132815	Toxicity	Inhibition of human ERG by patch-clamp assay	Homo sapiens	1	ALA5131397	assay format	Scientific Literature
9.	ALA5132816	Binding	Inhibition of ELOVL1 in human HEK293 cells assessed as reduction of C26:0 VLCFA synthesis incubated for 48 hrs by cellular assay	Homo sapiens	1	ALA5131397	cell-based format	Scientific Literature
10.	ALA5132817	Functional	Reduction in C26:0 LPC level in ABCD1 knock out mouse blood assessed as fold increase at 0.5 to 32 mg/kg, po qd for 105 days by LC-MS/MS analysis	Mus musculus	1	ALA5131397	organism-based format	Scientific Literature
11.	ALA5132818	ADME	AUC (infinity) in Sprague-Dawley rat at 3 mg/kg, po upto 24 hrs by LC/MS/MS analysis	Rattus norvegicus	1	ALA5131397	organism-based format	Scientific Literature
12.	ALA5132819	ADME	Volume of distribution at steady state in Beagle dog at 0.5 mg/kg, iv upto 48 hrs by LC/MS/MS analysis	Canis lupus familiaris	1	ALA5131397	organism-based format	Scientific Literature
13.	ALA5132820	ADME	Volume of distribution at steady state in Cynomolgus monkey at 1 mg/kg, iv upto 48 hrs by LC/MS/MS analysis	Macaca fascicularis	1	ALA5131397	organism-based format	Scientific Literature
14.	ALA5132821	ADME	Plasma protein binding in dog at 5 uM	Canis lupus familiaris	1	ALA5131397	cell-free format	Scientific Literature
15.	ALA5132822	Toxicity	Cytotoxicity against human THLE-2 cells assessed as decrease in intracellular ATP levels incubated for 72 hrs by Cell Titer-Glo luminescence assay	Homo sapiens	1	ALA5131397	cell-based format	Scientific Literature
16.	ALA5132823	Binding	Inhibition of ELOVL1 (unknown origin) using C22-acyl-CoA as substrate by radiometric enzyme assay	Homo sapiens	50	ALA5131397	single protein format	Scientific Literature
17.	ALA5132825	Binding	Inhibition of ELOVL7 (unknown origin) using C18-acyl-CoA as substrate by radiometric enzyme assay	Homo sapiens	4	ALA5131397	single protein format	Scientific Literature
18.	ALA5132826	Binding	Inhibition of ELOVL1 in human HEK2936E cells assessed as reduction of C26:0 LPC synthesis incubated for 48 hrs by cellular assay	Homo sapiens	47	ALA5131397	cell-based format	Scientific Literature
19.	ALA5132827	ADME	Intrinsic clearance in human hepatocytes assessed per million cells	Homo sapiens	47	ALA5131397	cell-based format	Scientific Literature
20.	ALA5132828	ADME	Intrinsic clearance in rat hepatocytes assessed per million cells	Rattus norvegicus	47	ALA5131397	cell-based format	Scientific Literature