# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5054466 | B | Inhibition of topoisomerase 1 (unknown origin) assessed as relaxation of supercoiled plasmid pUC18 measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 3 | ALA5053515 | single protein format | Scientific Literature | |
2. | ALA5054467 | B | Inhibition of human topoisomerase 2a assessed as reduction in decatenation of kinetoplast DNA at 25 uM using kinetoplast DNA as substrate incubated for 2 hrs by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 3 | ALA5053515 | single protein format | Scientific Literature | |
3. | ALA5054469 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured at 48 hrs by resazurin reagent based assay | Homo sapiens | 5 | ALA5053515 | cell-based format | Scientific Literature | |
4. | ALA5054470 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 100 uM measured at 48 hrs by resazurin reagent based assay relative to control | Homo sapiens | 1 | ALA5053515 | cell-based format | Scientific Literature | |
5. | ALA5054471 | F | Cytotoxicity against human CCF-STTG1 cells assessed as reduction in cell viability measured at 48 hrs by resazurin reagent based assay | Homo sapiens | 6 | ALA5053515 | cell-based format | Scientific Literature |