# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5032051 | B | Inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes at 100 uM by qRT-PCR analysis | Ricinus communis | 14 | ALA5030555 | single protein format | Scientific Literature | |
2. | ALA5032052 | B | Binding affinity to castor beans ricin toxin A subunit assessed as dissociation constant by surface plasmon resonance analysis | Ricinus communis | 14 | ALA5030555 | single protein format | Scientific Literature | |
3. | ALA5032053 | B | Potency index, ratio of CC10501 to test compound IC50 for inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 4 | ALA5030555 | single protein format | Scientific Literature | |
4. | ALA5032054 | B | Inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | single protein format | Scientific Literature | |
5. | ALA5032055 | B | Maximal inhibition of castor beans ricin toxin A subunit assessed as depurination of ribosome using yeast ribosomes by qRT-PCR analysis | Ricinus communis | 4 | ALA5030555 | single protein format | Scientific Literature | |
6. | ALA5032056 | B | Inhibition of castor bean ricin mediated depurination activity African green monkey Vero cells toxin pretreated for 2 hrs at 250 uM measured after 2 hrs of cell addition by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | cell-based format | Scientific Literature | |
7. | ALA5032057 | B | Inhibition of castor bean ricin mediated depurination activity African green monkey Vero cells toxin pretreated for 2 hrs at 500 uM measured after 2 hrs of cell addition by qRT-PCR analysis | Ricinus communis | 5 | ALA5030555 | cell-based format | Scientific Literature | |
8. | ALA5032058 | F | Protection against ricin holo-toxin (unknown origin)-induced african green monkey Vero cell death assessed as increase in cell viability at 500 uM measured after 24 hrs by Cell-Titre Glo luminescent viability assay | Chlorocebus sabaeus | 3 | ALA5030555 | cell-based format | Scientific Literature | |
9. | ALA5032059 | B | Inhibition of Escherichia coli Stx2a using african green monkey Vero cell assessed as inhibition of depurination incubated pretreated cells for 1 hr measured after 2 hrs of toxin addition | Escherichia coli | 4 | ALA5030555 | cell-based format | Scientific Literature | |
10. | ALA5032060 | F | Protection against Escherichia coli Stx2a-induce d african green monkey Vero cell death assessed as protection of cell viability incubated pretreated cells for 1 hr measured after 2 hrs of toxin addition | Chlorocebus sabaeus | 4 | ALA5030555 | cell-based format | Scientific Literature |