# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5056369 | Binding | Binding affinity to His6-tagged CypA (unknown origin) expressed in Escherichia coli BL21 (DE3) incubation at 1 hr by multimode plate reader | Homo sapiens | 11 | ALA5055636 | assay format | Scientific Literature | |
2. | ALA5056371 | ADME | Cytotoxicity against mouse HT-22 cells assessed as cell viability at 50 uM measured after 24 hrs by MTT assay | Mus musculus | 2 | ALA5055636 | cell-based format | Scientific Literature | |
3. | ALA5056372 | Functional | Neuroprotective activity against glutamine-induced toxicity in mouse HT-22 cells assessed as increase in survival at 50 uM preincubated for 24 hrs followed by glutamine addition and measured after 16 hrs by MTT assay | Mus musculus | 1 | ALA5055636 | cell-based format | Scientific Literature | |
4. | ALA5056374 | ADME | Stability of the compound in human serum assessed as compound remaining after 12 hrs by RP-HPLC analysis | Homo sapiens | 1 | ALA5055636 | cell-free format | Scientific Literature | |
5. | ALA5056375 | ADME | Stability of the compound in human serum after 2 hrs by RP-HPLC analysis | Homo sapiens | 1 | ALA5055636 | cell-free format | Scientific Literature |