# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA618310 | A | Unbound fraction (plasma) | Homo sapiens | 120 | cell-free format | Scientific Literature | ||
2. | ALA624569 | A | Observed volume of distribution | Homo sapiens | 120 | organism-based format | Scientific Literature | ||
3. | ALA633292 | P | Ionization constant (pKa) | 80 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA1963912 | F | PUBCHEM_BIOASSAY: S16 Schwann cell viability assay (CellTiter-Glo assay). (Class of assay: confirmatory) | 515 | cell-based format | PubChem BioAssays | |||
5. | ALA1614670 | A | Volume of distribution at steady state in human after iv administration | Homo sapiens | 667 | organism-based format | Scientific Literature | ||
6. | ALA1614671 | A | Clearance in human after iv administration | Homo sapiens | 667 | organism-based format | Scientific Literature | ||
7. | ALA1614672 | A | Fraction unbound in human after iv administration | Homo sapiens | 554 | organism-based format | Scientific Literature | ||
8. | ALA1614673 | A | Mean residence time in human after iv administration | Homo sapiens | 667 | organism-based format | Scientific Literature | ||
9. | ALA1614674 | A | Half life in human after iv administration | Homo sapiens | 667 | organism-based format | Scientific Literature | ||
10. | ALA2449009 | P | pKa (acid-base dissociation constant) as determined by Luan ref: Pharm. Res. 2005 | 67 | small-molecule physicochemical format | Scientific Literature | |||
11. | ALA3279116 | F | In vivo inhibition of beta-1 adrenergic receptor in iv dosed cat assessed as inhibition of isoproterenol-induced trachycardia after 30 mins | Felis catus | 39 | organism-based format | Scientific Literature | ||
12. | ALA3279118 | F | In vivo inhibition of beta-2 adrenergic receptor in iv dosed cat assessed as inhibition of isoproterenol-induced vasodepressor response after 30 mins | Felis catus | 36 | organism-based format | Scientific Literature | ||
13. | ALA3280054 | F | Inhibition of isoproterenol-induced tachycardia in anesthetized cat compound administered as an infusion over a period of 30 mins | Felis catus | 43 | organism-based format | Scientific Literature | ||
14. | ALA3280055 | A | Inhibition of isoproterenol-induced vasodepressor response in anesthetized cat compound administered as an infusion over a period of 30 mins | Felis catus | 39 | organism-based format | Scientific Literature | ||
15. | ALA4303805 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
16. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
17. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
18. | ALA4651403 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | organism-based format | IMI-CARE SARS-CoV-2 Data | ||
19. | ALA4808149 | B | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 | ||
20. | ALA4808150 | B | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | single protein format | Fraunhofer HDAC6 |