# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5044259 | Functional | Induction of apoptosis in human KYSE-450 cells assessed as caspase-3 cleavage at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
2. | ALA5044260 | Functional | Induction of mitochondrial membrane potential loss in human KYSE-30 cells assessed as upregulation of NOXA protein at 80 to 100 nM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
3. | ALA5044261 | Functional | Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay | Homo sapiens | 39 | ALA5042512 | cell-based format | Scientific Literature | |
4. | ALA5044262 | Functional | Antiproliferative activity against human KYSE-450 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay | Homo sapiens | 39 | ALA5042512 | cell-based format | Scientific Literature | |
5. | ALA5044263 | Functional | Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition measured after 48 hrs by CCK8 assay | Homo sapiens | 39 | ALA5042512 | cell-based format | Scientific Literature | |
6. | ALA5044264 | Binding | Inhibition of pig brain tubulin polymerization at 3 uM by spectrophotometry | Sus scrofa | 1 | ALA5042512 | assay format | Scientific Literature | |
7. | ALA5044265 | Binding | Inhibition of tubulin polymerization in human KYSE-30 cells assessed as microtubule assembly at 0.1 uM measured after 48 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
8. | ALA5044266 | Binding | Inhibition of tubulin polymerization in human KYSE-450 cells assessed as microtubule assembly at 0.1 uM measured after 48 hrs by immunofluorescence assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
9. | ALA5044267 | Binding | Inhibition of tubulin polymerization in human KYSE-30 cells assessed as weakening of beta tubulin at 100 to 300 nM for 2 hrs by EBI alkylate competition assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
10. | ALA5044268 | Binding | Inhibition of tubulin polymerization in human KYSE-450 cells assessed as weakening of beta tubulin at 100 to 300 nM for 2 hrs by EBI alkylate competition assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
11. | ALA5044269 | Functional | Antiproliferative activity against human KYSE-30 cells assessed as cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
12. | ALA5044270 | Functional | Antiproliferative activity against human KYSE-450 cells assessed as cell viability measured after 48 hrs by CCK8 assay | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
13. | ALA5044271 | Functional | Antiproliferative activity against human KYSE-30 cells assessed as inhibition of colony formation at 40 to 60 nM for 7 days by crystal violet staining based analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
14. | ALA5044272 | Functional | Antiproliferative activity against human KYSE-450 cells assessed as inhibition of colony formation at 40 to 60 nM for 7 days by crystal violet staining based analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
15. | ALA5044273 | Functional | Induction of cell cycle arrest in human KYSE-30 cells assessed as accumulation at G2/M phase at 100 nM measured after 48 hrs by flow cytometry analysis (Rvb = 19.38 %) | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
16. | ALA5044274 | Functional | Induction of cell cycle arrest in human KYSE-450 cells assessed as accumulation at G2/M phase at 100 nM measured after 48 hrs by flow cytometry analysis (Rvb = 7.04333 %) | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
17. | ALA5044275 | Functional | Down regulation of CDK1 protein expression in human KYSE-30 cells at 80 to 100 nM for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
18. | ALA5044276 | Functional | Down regulation of CDK1 protein expression in human KYSE-450 cells at 80 to 100 nM for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
19. | ALA5044277 | Functional | Down regulation of CDC25C protein expression in human KYSE-30 cells at 80 to 100 nM for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature | |
20. | ALA5044278 | Functional | Down regulation of CDC25C protein expression in human KYSE-450 cells at 80 to 100 nM for 48 hrs by western blot analysis | Homo sapiens | 1 | ALA5042512 | cell-based format | Scientific Literature |