| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5042060 | T | Induction of apoptosis in mouse BaF3 cells assessed as survival population at 1 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry(Rvb = 96.35 %) | Mus musculus | 1 | ALA5038665 | cell-based format | Scientific Literature | |
| 2. | ALA5042061 | T | Induction of apoptosis in mouse BaF3 cells assessed as survival population at 0.5 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry(Rvb = 96.35 %) | Mus musculus | 1 | ALA5038665 | cell-based format | Scientific Literature | |
| 3. | ALA5042062 | T | Induction of apoptosis in mouse BaF3 cells assessed as survival population at 0.1 uM measured after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry(Rvb = 96.35 %) | Mus musculus | 1 | ALA5038665 | cell-based format | Scientific Literature | |
| 4. | ALA5042063 | A | Oral bioavailability in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 5. | ALA5042064 | A | Clearance in 12 hrs fasted Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 6. | ALA5042065 | A | AUC (0-t) in 12 hrs fasted Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 7. | ALA5042066 | A | AUC (0-t) in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg, po measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 8. | ALA5042067 | A | Clearance in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg, po measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 9. | ALA5042068 | A | Half life in 12 hrs fasted Sprague-Dawley rat at 2 mg/kg, iv measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 10. | ALA5042069 | A | Half life in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg, po measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 11. | ALA5042070 | A | Cmax in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg, po measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 12. | ALA5042071 | F | Antiproliferative activity against human ML-1 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 6 | ALA5038665 | cell-based format | Scientific Literature | |
| 13. | ALA5042072 | A | Tmax in 12 hrs fasted Sprague-Dawley rat at 15 mg/kg, po measured upto 24 hrs by LC-MS analysis | Rattus norvegicus | 1 | ALA5038665 | organism-based format | Scientific Literature | |
| 14. | ALA5042073 | F | Antiproliferative activity against human HL-60 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 6 | ALA5038665 | cell-based format | Scientific Literature | |
| 15. | ALA5042074 | T | Antiproliferative activity against mouse BaF3 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Mus musculus | 4 | ALA5038665 | cell-based format | Scientific Literature | |
| 16. | ALA5042075 | F | Antiproliferative activity against human MOLM-13 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 4 | ALA5038665 | cell-based format | Scientific Literature | |
| 17. | ALA5042076 | F | Antiproliferative activity against mouse Ba/F3 FLT3-ITD cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Mus musculus | 4 | ALA5038665 | cell-based format | Scientific Literature | |
| 18. | ALA5042077 | F | Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs ny MTS assay | Homo sapiens | 4 | ALA5038665 | cell-based format | Scientific Literature | |
| 19. | ALA5042078 | B | Inhibition of BRAF (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
| 20. | ALA5042079 | B | Inhibition of FGFR1 (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature |
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