| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5044552 | B | Inhibition of BRD3 D1 (unknown origin) at 50 uM by competitive fluorescence anisotropy assay relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 2. | ALA5044553 | B | Inhibition of BRD4 D1 (unknown origin) by competitive fluorescence anisotropy assay | Homo sapiens | 33 | single protein format | Scientific Literature | ||
| 3. | ALA5044555 | B | Inhibition of BRDT D1 (unknown origin) at 50 uM by competitive fluorescence anisotropy assay relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 4. | ALA5044556 | B | Binding affinity to wild-type human full length p38-alpha (M1 to S360 residues) expressed in bacterial expression system by Kinomescan method | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 5. | ALA5044557 | B | Inhibition of BRD2 D1 (unknown origin) at 50 uM by competitive fluorescence anisotropy assay relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 6. | ALA5044558 | F | Cytotoxicity against human A549 cells assessed as viable cells incubated for 23 hrs by alamar blue assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA5044559 | F | Anti-inflammatory activity in human A549 cells assessed as residual IL-8 levels at 1 uM preincubated for 6 hrs followed by TNFalpha induction and measured after 24 hrs by ELISA | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA5044560 | T | Cytotoxicity against human liver sinusoidal endothelial cells assessed as viable cells incubated for 20 to 24 hrs by XTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5044561 | F | Anti-inflammatory activity in human liver sinusoidal endothelial cells assessed as residual CCL2 mRNA levels at 1.3 uM incubated for 2 hrs followed by LPS induction for 4 hrs by SYBR green staining based qRT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5044562 | F | Anti-inflammatory activity in human liver sinusoidal endothelial cells assessed as residual CXCL1 mRNA levels at 1.3 uM incubated for 2 hrs followed by LPS induction for 4 hrs by SYBR green staining based qRT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA5044566 | B | Inhibition of BRD2 D2 (unknown origin) by competitive fluorescence anisotropy assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA5044567 | B | Inhibition of BRD3 D2 (unknown origin) by competitive fluorescence anisotropy assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA5044568 | B | Inhibition of BRD4 D2 (unknown origin) by competitive fluorescence anisotropy assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA5044569 | B | Binding affinity to BRD2 D1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA5044570 | B | Binding affinity to BRD4 D1 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA5044571 | B | Binding affinity to BRD4 D2 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA5044572 | B | Binding affinity to wild-type human partial length EGFR (R669 to V1011 residues) expressed in bacterial expression system at 1 uM by Kinomescan method relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA5044574 | B | Binding affinity to BRD2 in human MM1.S cells upto 25 uM treated for 1 hr by cellular thermal shift assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA5044575 | F | Downregulation of c-Myc expression level in human MM1.S cells at lower concentration treated for 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5044576 | F | Downregulation of c-Myc expression level in human MM1.S cells at higher concentration treated for 6 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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