# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053346 | B | Inhibition of 50 nM of HSD17B13 (unknown origin) using LTB4 as substrate incubated for 1 or 2 hrs and measured after 1 hr by NADH Glo luminescence assay | Homo sapiens | 564 | assay format | Patent Bioactivity Data | ||
2. | ALA5053347 | A | Half-life in human liver microsomes at 1 uM incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Homo sapiens | 85 | microsome format | Patent Bioactivity Data | ||
3. | ALA5053348 | A | Clearance in human liver microsomes at 1 uM incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Homo sapiens | 85 | microsome format | Patent Bioactivity Data | ||
4. | ALA5053349 | A | Metabolic stability in human liver microsomes at 1 uM assessed as compound remaining incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Homo sapiens | 85 | microsome format | Patent Bioactivity Data | ||
5. | ALA5053350 | A | Half-life in mouse liver microsomes at 1 uM incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Mus musculus | 58 | microsome format | Patent Bioactivity Data | ||
6. | ALA5053351 | A | Clearance in mouse liver microsomes at 1 uM incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Mus musculus | 58 | microsome format | Patent Bioactivity Data | ||
7. | ALA5053352 | A | Metabolic stability in mouse liver microsomes at 1 uM assessed as compound remaining incubated for 60 mins followed by NADPH generating system addition and measured by LC-MS/MS analysis | Mus musculus | 58 | microsome format | Patent Bioactivity Data | ||
8. | ALA5053353 | B | Inhibition of HSD17B1 (unknown origin) using estradiol as substrate incubated for 3 hrs and measured after 1 hr by NADH Glo luminescence assay | Homo sapiens | 96 | single protein format | Patent Bioactivity Data | ||
9. | ALA5053354 | B | Inhibition of HSD17B2 (unknown origin) using estradiol as substrate incubated for 45 mins and measured after 1 hr by NADH Glo luminescence assay | Homo sapiens | 113 | single protein format | Patent Bioactivity Data | ||
10. | ALA5053355 | B | Inhibition of HSD17B4 (unknown origin) using estradiol as substrate incubated for 45 mins and measured after 1 hr by NADH Glo luminescence assay | Homo sapiens | 15 | single protein format | Patent Bioactivity Data | ||
11. | ALA5053356 | B | Inhibition of HSD17B10 (unknown origin) using estradiol as substrate incubated for 3 hrs and measured after 1 hr by NADH Glo luminescence assay | Homo sapiens | 15 | single protein format | Patent Bioactivity Data |