# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5049235 | Binding | Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluorimetric analysis | Homo sapiens | 12 | ALA5046287 | single protein format | Scientific Literature | |
2. | ALA5049236 | Binding | Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluorimetric analysis | Homo sapiens | 6 | ALA5046287 | single protein format | Scientific Literature | |
3. | ALA5049237 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH1A1 at 10 uM in presence of NADH by fluorimetric analysis relative to hexanal | Homo sapiens | 5 | ALA5046287 | single protein format | Scientific Literature | |
4. | ALA5049238 | Binding | Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as remaining enzyme activity by measuring fluorescence of NADPH using 4-NBA and NADP+ as substrate at 10 uM by fluorimetric analysis relative to control | Homo sapiens | 6 | ALA5046287 | single protein format | Scientific Literature | |
5. | ALA5049241 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 at 10 uM in presence of NADPH by fluorimetric analysis relative to 4-NBA | Homo sapiens | 2 | ALA5046287 | single protein format | Scientific Literature | |
6. | ALA5049242 | Binding | Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysis | Homo sapiens | 2 | ALA5046287 | single protein format | Scientific Literature | |
7. | ALA5049243 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Km in presence of NADPH by fluorometric assay | Homo sapiens | 2 | ALA5046287 | single protein format | Scientific Literature | |
8. | ALA5049244 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Ksi in presence of NADPH by fluorometric assay | Homo sapiens | 1 | ALA5046287 | single protein format | Scientific Literature | |
9. | ALA5049245 | ADME | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Kcat in presence of NADPH by fluorometric assay | Homo sapiens | 2 | ALA5046287 | single protein format | Scientific Literature | |
10. | ALA5049246 | Functional | Antiproliferative activity against human PC-3 cells expressing ALDH1A1 and ALDH3A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature | |
11. | ALA5049247 | Functional | Antiproliferative activity against human LNCaP cells expressing ALDH1A3 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature | |
12. | ALA5049248 | Functional | Antiproliferative activity against human DU145 cells expressing ALDH1A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | ALA5046287 | cell-based format | Scientific Literature | |
13. | ALA5049249 | Functional | Cytotoxicity against human H415/15 cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | ALA5046287 | cell-based format | Scientific Literature | |
14. | ALA5049250 | Functional | Cytotoxicity against human H568/15 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | ALA5046287 | cell-based format | Scientific Literature | |
15. | ALA5049251 | Functional | Cytotoxicity against human H431/14 LM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | ALA5046287 | cell-based format | Scientific Literature | |
16. | ALA5049252 | Functional | Cytotoxicity against human H488/14 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | ALA5046287 | cell-based format | Scientific Literature | |
17. | ALA5049253 | Functional | Cytotoxicity against human H517/15 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | ALA5046287 | cell-based format | Scientific Literature | |
18. | ALA5049254 | Functional | Cytotoxicity against human H415/15 cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | ALA5046287 | cell-based format | Scientific Literature | |
19. | ALA5049255 | Functional | Cytotoxicity against human H568/15 RM cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | ALA5046287 | cell-based format | Scientific Literature | |
20. | ALA5049256 | Functional | Cytotoxicity against human H431/14 LM cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | ALA5046287 | cell-based format | Scientific Literature |