| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5049235 | B | Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluorimetric analysis | Homo sapiens | 12 | single protein format | Scientific Literature | ||
| 2. | ALA5049236 | B | Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluorimetric analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 3. | ALA5049237 | A | Substrate activity at N-terminal-His6 tagged recombinant human ALDH1A1 at 10 uM in presence of NADH by fluorimetric analysis relative to hexanal | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA5049238 | B | Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as remaining enzyme activity by measuring fluorescence of NADPH using 4-NBA and NADP+ as substrate at 10 uM by fluorimetric analysis relative to control | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 5. | ALA5049241 | A | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 at 10 uM in presence of NADPH by fluorimetric analysis relative to 4-NBA | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA5049242 | B | Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 7. | ALA5049243 | A | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Km in presence of NADPH by fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 8. | ALA5049244 | A | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Ksi in presence of NADPH by fluorometric assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA5049245 | A | Substrate activity at N-terminal-His6 tagged recombinant human ALDH3A1 assessed as Kcat in presence of NADPH by fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA5049246 | F | Antiproliferative activity against human PC-3 cells expressing ALDH1A1 and ALDH3A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 11. | ALA5049247 | F | Antiproliferative activity against human LNCaP cells expressing ALDH1A3 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 12. | ALA5049248 | F | Antiproliferative activity against human DU145 cells expressing ALDH1A1 assessed as reduction in cell survival measured after 96 hrs by MTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 13. | ALA5049249 | F | Cytotoxicity against human H415/15 cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA5049250 | F | Cytotoxicity against human H568/15 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA5049251 | F | Cytotoxicity against human H431/14 LM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA5049252 | F | Cytotoxicity against human H488/14 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA5049253 | F | Cytotoxicity against human H517/15 RM cells assessed as reduction in cell viability incubated for 72 hrs by AlamarBlue staining based analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA5049254 | F | Cytotoxicity against human H415/15 cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA5049255 | F | Cytotoxicity against human H568/15 RM cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA5049256 | F | Cytotoxicity against human H431/14 LM cells assessed as reduction in cell viability at 50 to 200 uM incubated for 72 hrs in presence of docetaxel by AlamarBlue staining based analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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