| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5030928 | A | Stability in human plasma assessed as half life measured upto 48 hrs by RP-HPLC analysis | Homo sapiens | 3 | cell-free format | Scientific Literature | ||
| 2. | ALA5030931 | A | Drug metabolism in 5 mM GSH assessed as 5-FU release after 4 hrs | 1 | assay format | Scientific Literature | |||
| 3. | ALA5030932 | A | Drug metabolism in 5 mM GSH assessed as 5-FU release after 48 hrs | 3 | assay format | Scientific Literature | |||
| 4. | ALA5030933 | A | Drug metabolism in 1 mM GSH assessed as 5-FU release after 4 hrs | 1 | assay format | Scientific Literature | |||
| 5. | ALA5030934 | P | Half life of the compound in 1 mM GSH | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 6. | ALA5030935 | P | Half life of the compound in 5 mM GSH | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5030936 | A | Drug degradation in 5 uM GSH after 48 hrs | 1 | assay format | Scientific Literature | |||
| 8. | ALA5030938 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 9. | ALA5030939 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 10. | ALA5030940 | F | Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 11. | ALA5030941 | F | Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 12. | ALA5030946 | A | Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA5030947 | F | Antitumour activity against human colorectal cancer cells xenografted in BALB/c mouse assessed as tumour suppression at 50 mg/kg, ip administered once every 3 days for 3 weeks | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 14. | ALA5030948 | T | Toxicity in BALB/c mouse xenografted with human colorectal cancer cells assessed as reduction in body weight at 50 mg/kg, ip administered once every 3 days for 3 weeks | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 15. | ALA5030950 | A | Drug metabolism in BALB/c mouse assessed as release of 5-FU in blood at 50 mg/kg, iv measured after 2 hrs by UPLC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5030951 | A | Drug uptake in BALB/c mouse blood at 50 mg/kg, iv measured after 30 mins by UPLC-MS/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5030952 | A | Drug uptake in BALB/c mouse blood at 50 mg/kg, iv measured after 45 mins by UPLC-MS/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5030953 | A | Drug uptake in BALB/c mouse blood at 50 mg/kg, iv measured after 4 hrs by UPLC-MS/MS method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5030954 | A | Tmax in BALB/c mouse at 50 mg/kg, ip by LC-MS/MS analysis | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA5030955 | A | Biodistribution in BALB/c mouse stomach at 50 mg/kg, ip measured after 1 hr | Mus musculus | 2 | organism-based format | Scientific Literature |
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