# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053929 | A | Cytotoxicity against BALB/c mouse peritoneal macrophages assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Mus musculus | 12 | cell-based format | Scientific Literature | ||
2. | ALA5053930 | F | Antileishmanial activity against Leishmania amazonensis (MHOM/BR/76/MA-76) promastigotes assessed as reduction in parasite growth incubated for 24 hrs by MTT assay | Leishmania amazonensis | 12 | organism-based format | Scientific Literature | ||
3. | ALA5053931 | T | Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse peritoneal macrophages to IC50 for antileishmanial activity against Leishmania amazonensis (MHOM/BR/76/MA-76) promastigotes | 12 | assay format | Scientific Literature | |||
4. | ALA5053932 | F | Antileishmanial activity against Leishmania amazonensis (MHOM/BR/76/MA-76) intracellular amastigotes infected in BALB/c mouse peritoneal macrophages assessed as reduction in parasite growth incubated for 24 hrs by Giemsa's azur-eosin-methyle blue staining based light microscopy analysis | Leishmania amazonensis | 12 | organism-based format | Scientific Literature | ||
5. | ALA5053933 | T | Selectivity index, ratio of CC50 for cytotoxicity against BALB/c mouse peritoneal macrophage to IC50 for antileishmanial activity against Leishmania amazonensis (MHOM/BR/76/MA-76) intracellular amastigotes infected in BALB/c mouse peritoneal macrophages | 12 | cell-based format | Scientific Literature | |||
6. | ALA5053934 | A | Cytotoxicity against human CCD-1072Sk cells assessed as reduction in cell viability at <400 uM measured after 24 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature |