# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5045598 | B | Inhibition of sigma 2 receptor (unknown origin) assessed as binding constant | Homo sapiens | 17 | single protein format | Scientific Literature | ||
2. | ALA5045600 | P | Aqueous solubility of the compound at pH 4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA5045601 | B | Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy 6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate addition and measured after 30 mins by BD FACSCalibur flow cytometry analysis | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
4. | ALA5045602 | P | Aqueous solubility of the compound at pH 7.4 | 32 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA5045603 | P | Distribution coefficient, logD of compound at pH 7.4 by HPLC analysis | 33 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA5045604 | B | Inhibition of fluorescent antagonist binding to mouse P2Y14R expressed in HEK293 cells preincubated for 30 mins followed by addition of 6-amino-9-(2-carboxy-4-((6-(4-(4-(4-(4-(3-carboxy-6-(4-(trifluoromethyl)phenyl)naphthalen-1-yl)phenyl)piperidin-1-yl)butyl)-1H-1,2,3-triazol-1-yl)hexyl)carbamoyl)phenyl)-3-iminio-5-sulfo-3H-xanthene-4-sulfonate incubated for 30 mins by BD FACSCalibur flow cytometry analysis | Mus musculus | 10 | cell-based format | Scientific Literature | ||
7. | ALA5045613 | B | Inhibition of adrenergic alpha 2B receptor (unknown origin) assessed as binding constant | Homo sapiens | 7 | single protein format | Scientific Literature | ||
8. | ALA5045615 | A | Stability of the compound in simulated intestinal fluid assessed as parent compound remaining at 120 mins | 2 | assay format | Scientific Literature | |||
9. | ALA5045616 | A | Stability of the compound in simulated gastric fluid assessed as parent compound remaining at 120 mins by NMR analysis | 2 | assay format | Scientific Literature | |||
10. | ALA5045617 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
11. | ALA5045618 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
12. | ALA5045619 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
13. | ALA5045620 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA5045621 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA5045622 | A | Stability in rat plasma assessed as compound remaining after 120 mins | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
16. | ALA5045623 | A | Stability in mouse plasma assessed as compound remaining after 120 mins | Mus musculus | 2 | cell-free format | Scientific Literature | ||
17. | ALA5045624 | A | Stability in mouse liver microsomes assessed as half life | Mus musculus | 2 | microsome format | Scientific Literature | ||
18. | ALA5045625 | A | Stability in rat liver microsomes assessed as half life | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
19. | ALA5045626 | A | Stability in human liver microsomes assessed as half life | Homo sapiens | 2 | microsome format | Scientific Literature | ||
20. | ALA5045627 | T | Inhibition of hERG channel by patch clamp assay | Homo sapiens | 2 | assay format | Scientific Literature |