# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5045272 | Binding | Inhibition of mouse MAGL using 2-AG as substrate incubated for 30 mins | Mus musculus | 21 | ALA5042536 | single protein format | Scientific Literature | |
2. | ALA5045273 | Physicochemical | Distribution coefficient between 1-octanol and phosphate buffer, logD of the compound after 15 mins by shake flask assay | 3 | ALA5042536 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA5045274 | ADME | Drug uptake in Wistar rat brain striatum at 2 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
4. | ALA5045275 | ADME | Drug uptake in Wistar rat brain Hippocampus at 2 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
5. | ALA5045276 | ADME | Drug uptake in Wistar rat brain Cortex at 2 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
6. | ALA5045277 | ADME | Drug uptake in Wistar rat brain Thalamus at 2 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
7. | ALA5045278 | ADME | Drug uptake in Wistar rat brain Cerebellum at 2 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
8. | ALA5045279 | ADME | Drug uptake in Wistar rat brain striatum at 5 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
9. | ALA5045280 | ADME | Drug uptake in Wistar rat brain Hippocampus at 5 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
10. | ALA5045281 | ADME | Drug uptake in Wistar rat brain Cortex at 5 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
11. | ALA5045282 | ADME | Drug uptake in Wistar rat brain Thalamus at 5 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
12. | ALA5045283 | ADME | Drug uptake in Wistar rat brain Cerebellum at 5 nM incubated for 30 mins by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
13. | ALA5045284 | ADME | Drug uptake in Wistar rat brain incubated for 30 mins in presence of SAR127303 by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
14. | ALA5045285 | ADME | Drug uptake in Wistar rat brain incubated for 30 mins in presence of PF-06809247 by autoradiography | Rattus norvegicus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
15. | ALA5045286 | ADME | Drug uptake in MAGL knockout mouse brain incubated for 30 mins by autoradiography relative to control | Mus musculus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
16. | ALA5045287 | ADME | Drug uptake in C5BL/6 mouse brain incubated for 30 mins by autoradiography | Mus musculus | 2 | ALA5042536 | tissue-based format | Scientific Literature | |
17. | ALA5045336 | ADME | Drug uptake in C57BL/6 mouse brain at 4.41 to 6.8 nmol/kg, iv and measured after 1 min post infection by PET imaging anlaysis | Mus musculus | 2 | ALA5042536 | organism-based format | Scientific Literature |