#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5046919	F	Antitumor activity against JAK2V6175 transgenic myelofibrosis C57BL/6 mouse cancer model assessed as reduction in spleen volume at 325 mg/kg, po administered daily for 4 days by magnetic resonance imaging analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature
2.	ALA5046920	F	Effect of MAPK signalling pathway in JAK2V6175 transgenic myelofibrosis C57BL/6 mouse spleen assessed as reduction in AKT phosphorylation at 325 mg/kg, po administered daily for 5 days by flow cytometry analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature
3.	ALA5046921	A	Drug metabolism in JAK2V6175 transgenic myelofibrosis C57BL/6 mouse blood at 325 mg/kg, po assessed as metabolite formation measured after 4 hrs by LC-MS/MS analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature
4.	ALA5046922	B	Inhibition of human PI3Kalpha by TR-FRET based Adapta assay	Homo sapiens	18	ALA5046229	single protein format	Scientific Literature
5.	ALA5046923	B	Inhibition of human PI3Kbeta by TR-FRET based Adapta assay	Homo sapiens	18	ALA5046229	single protein format	Scientific Literature
6.	ALA5046924	B	Inhibition of human PI3Kgamma by TR-FRET based Adapta assay	Homo sapiens	18	ALA5046229	single protein format	Scientific Literature
7.	ALA5046925	B	Inhibition of human PI3Kdelta by TR-FRET based Adapta assay	Homo sapiens	18	ALA5046229	single protein format	Scientific Literature
8.	ALA5046926	B	Inhibition of human MEK-1 by Lanthascreen TR-FRET assay	Homo sapiens	3	ALA5046229	single protein format	Scientific Literature
9.	ALA5046927	F	Antiproliferative activity against human A-375 cells assessed as reduction in cell viability measured after 72 hrs by CellTiter-Fluor cell viability assay	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
10.	ALA5046928	F	Antiproliferative activity against human D54 cells assessed as reduction in cell viability measured after 72 hrs by CellTiter-Fluor cell viability assay	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
11.	ALA5046929	F	Antiproliferative activity against human SET-2 cells assessed as reduction in cell viability measured after 72 hrs by CellTiter-Fluor cell viability assay	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
12.	ALA5046930	B	Inhibition of ERK phosphorylation in human A-375 cells assessed as change in phosphorylated ERK level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
13.	ALA5046931	B	Inhibition of AKT phosphorylation in human A-375 cells assessed as change in phosphorylated Akt level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
14.	ALA5046932	B	Inhibition of ERK phosphorylation in human D-54 cells assessed as change in phosphorylated ERK level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
15.	ALA5046933	B	Inhibition of AKT phosphorylation in human D-54 cells assessed as change in phosphorylated Akt level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
16.	ALA5046934	B	Inhibition of ERK phosphorylation in human SET2 cells assessed as change in phosphorylated ERK level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
17.	ALA5046935	B	Inhibition of AKT phosphorylation in human SET2 cells assessed as change in phosphorylated Akt level at 10 uM for 30 minutes in presence of PDGF by western blot analysis relative to control	Homo sapiens	2	ALA5046229	cell-based format	Scientific Literature
18.	ALA5046936	F	Effect of MAPK signalling pathway in JAK2V6175F transgenic myelofibrosis C57BL/6 mouse spleen assessed as reduction in ERK1/2 phosphorylation at 325 mg/kg, po daily for 5 days by flow cytometry analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature
19.	ALA5046937	F	Effect of PI3K signalling pathway in JAK2V6175 transgenic myelofibrosis C57BL/6 mouse spleen assessed as reduction in ERK1/2 phosphorylation at 325 mg/kg, po administered daily for 5 days by flow cytometry analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature
20.	ALA5046938	F	Effect of PI3K signalling pathway in JAK2V6175 transgenic myelofibrosis C57BL/6 mouse spleen assessed as reduction in AKT phosphorylation at 325 mg/kg, po administered daily for 5 days by flow cytometry analysis	Mus musculus	2	ALA5046229	organism-based format	Scientific Literature