| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5038057 | B | Inhibition of Mycobacterium tuberculosis Pks13-TE domain using 4-methylumbelliferyl heptanoate as a fluorogenic substrate measured for 110 mins at 10 mins interval | Mycobacterium tuberculosis | 38 | single protein format | Scientific Literature | ||
| 2. | ALA5038058 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv | Mycobacterium tuberculosis | 38 | organism-based format | Scientific Literature | ||
| 3. | ALA5038059 | F | Antimycobacterial activity against Mycobacterium tuberculosis infected in THP1 monocytes assessed as inhibition of luciferase luminescence signal | Mycobacterium tuberculosis | 10 | organism-based format | Scientific Literature | ||
| 4. | ALA5038061 | B | Inhibition of hERG ion channel by Q patch-clamp method | Homo sapiens | 37 | single protein format | Scientific Literature | ||
| 5. | ALA5038063 | A | Intrinsic microsomal clearance in CDI mouse liver microsomes | Mus musculus | 38 | microsome format | Scientific Literature | ||
| 6. | ALA5038064 | P | Lipophilicity, CHI-log D of the compound at pH 7.4 by HPLC-UV analysis | 38 | small-molecule physicochemical format | Scientific Literature | |||
| 7. | ALA5038068 | A | Cmax in CD1 mouse plasma at 70 mg/kg measured after 24 hrs | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 8. | ALA5038071 | A | AUC in CD1 mouse plasma at 70 mg/kg measured after 24 hrs | Mus musculus | 8 | organism-based format | Scientific Literature | ||
| 9. | ALA5038088 | F | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv intratracheally infected in C57BL/6 mouse assessed as 2 log10 reduction in colony forming unit at 70 mg/kg once daily for 8 days post infection | Mycobacterium tuberculosis | 9 | organism-based format | Scientific Literature |
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