# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5049001 | B | Inhibition of Escherichia coli NDM-1 using fluorocillin as substrate incubated for 30 mins by fluorescence based assay | Escherichia coli | 23 | assay format | Scientific Literature | ||
2. | ALA5049002 | B | Inhibition of Escherichia coli IMP-7 using fluorocillin as substrate incubated for 30 mins by fluorescence based assay | Escherichia coli | 23 | assay format | Scientific Literature | ||
3. | ALA5049003 | B | Inhibition of Escherichia coli VIM-1 using fluorocillin as substrate incubated for 30 mins by fluorescence based assay | Escherichia coli | 23 | single protein format | Scientific Literature | ||
4. | ALA5049004 | P | Lipophilicity, log D of the compound at pH 7.4 by HPLC-MS analysis | 23 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA5049005 | B | Inhibition of human MMP-1 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA5049006 | B | Inhibition of human MMP-2 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
7. | ALA5049007 | B | Inhibition of human MMP-3 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
8. | ALA5049008 | B | Inhibition of human MMP-7 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
9. | ALA5049009 | B | Inhibition of human MMP-8 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
10. | ALA5049010 | B | Inhibition of human MMP-14 at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
11. | ALA5049011 | B | Inhibition of human TACE at 100 uM relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
12. | ALA5049014 | F | Antibacterial activity against NDM-1 expressing Escherichia coli isolates assessed as inhibition of bacterial growth by microdilution method | Escherichia coli | 8 | organism-based format | Scientific Literature | ||
13. | ALA5049015 | F | Antibacterial activity against VIM-1 expressing Escherichia coli isolates assessed as inhibition of bacterial growth by microdilution method | Escherichia coli | 8 | organism-based format | Scientific Literature | ||
14. | ALA5049016 | F | Antibacterial activity against IMP-1 expressing Escherichia coli isolates assessed as inhibition of bacterial growth by microdilution method | Escherichia coli | 8 | organism-based format | Scientific Literature | ||
15. | ALA5049017 | F | Antibacterial activity against VIM-2 expressing Pseudomonas aeruginosa isolates assessed as inhibition of bacterial growth by microdilution method | Pseudomonas aeruginosa | 8 | organism-based format | Scientific Literature | ||
16. | ALA5049018 | T | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 100 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
17. | ALA5049019 | T | Cytotoxicity against human HEK293 cells assessed as reduction in cell viability at 100 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
18. | ALA5049020 | T | Cytotoxicity against human A549 cells assessed as reduction in cell viability at 100 uM relative to control | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
19. | ALA5049021 | T | Toxicity in zebrafish embryo assessed as maximum tolerated concentration measured up to 120 hrs | Danio rerio | 3 | assay format | Scientific Literature |