# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5042863 | Binding | Displacement of [125I]-1DMeNPFF from recombinant human NPFF1 receptor expressed in CHO cells by TopCount scintillation counting method | Homo sapiens | 24 | ALA5042475 | cell-based format | Scientific Literature | |
2. | ALA5042864 | Binding | Displacement of [125I]-1DMeNPFF from recombinant human NPFF2 receptor expressed in CHO cells by TopCount scintillation counting method | Homo sapiens | 24 | ALA5042475 | cell-based format | Scientific Literature | |
3. | ALA5042865 | Binding | Selectivity ratio of Ki for displacement of [125I]-1DMeNPFF from human NPFF2 receptor expressed in CHO cells to Ki for displacement of [125I]-1DMeNPFF from human NPFF1 receptor expressed in CHO cells | Homo sapiens | 24 | ALA5042475 | cell-based format | Scientific Literature | |
4. | ALA5042866 | Binding | Displacement of [125I]-1DMeNPFF from mouse NPFF1 receptor by TopCount scintillation counting method | Mus musculus | 6 | ALA5042475 | assay format | Scientific Literature | |
5. | ALA5042867 | Binding | Displacement of [125I]-1DMeNPFF from mouse NPFF2R receptor by TopCount scintillation counting method | Mus musculus | 6 | ALA5042475 | single protein format | Scientific Literature | |
6. | ALA5042868 | Binding | Selectivity ratio of Ki for displacement of [125I]-1DMeNPFF from mouse NPFF2 receptor to Ki for displacement of [125]-1DMeNPFF from mouse NPFF1 receptor | Mus musculus | 4 | ALA5042475 | assay format | Scientific Literature | |
7. | ALA5042869 | Binding | Displacement of [3H]-PrRP-20 from human PrRP receptor expressed in CHO cells by TopCount scintillation counting method | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
8. | ALA5042870 | Binding | Displacement of [125I]-Kp-10 from human Kiss1 receptor by TopCount scintillation counting method | Homo sapiens | 11 | ALA5042475 | single protein format | Scientific Literature | |
9. | ALA5042871 | Binding | Displacement of [125I]-43RFa from human QRFP receptor expressed in CHO cells by TopCount scintillation counting method | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
10. | ALA5042872 | Binding | Displacement of [3H]-Diprenorphine from human MOP receptor expressed in HEK293 cells by scintillation counting method | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
11. | ALA5042873 | Binding | Displacement of [3H]-Diprenorphine from human DOP receptor expressed in HEK293 cells by scintillation counting method | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
12. | ALA5042874 | Binding | Displacement of [3H]-Diprenorphine from human KOP receptor expressed in HEK293 cells by scintillation counting method | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
13. | ALA5042875 | Binding | Displacement of [3H]nociceptin from human recombinant NOP receptor expressed in HEK293 cells by scintillation counting analysis | Homo sapiens | 11 | ALA5042475 | cell-based format | Scientific Literature | |
14. | ALA5042876 | Functional | Agonist activity at human NPFF1 receptor expressed in HEK293 cells assessed as reduction in forskolin- stimulated cAMP level upto 10 uM | Homo sapiens | 2 | ALA5042475 | cell-based format | Scientific Literature | |
15. | ALA5042877 | Functional | Antagonist activity at human NPFF1 receptor expressed in HEK293 cells assessed as rightward shift of the dose dependent curve of (S)-N1-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-((S)-1-((S)-2-((S)-4-amino-2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidine-2-carboxamido)-4-oxobutanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamido)pentanediamide | Homo sapiens | 2 | ALA5042475 | cell-based format | Scientific Literature | |
16. | ALA5042878 | Binding | Binding affinity to human NPFF1 receptor expressed in HEK293 cells assessed as rightward shift of the dose dependent curve of (S)-N1-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-5-guanidino-1-oxopentan-2-yl)-2-((S)-1-((S)-2-((S)-4-amino-2-((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidine-2-carboxamido)-4-oxobutanamido)-4-methylpentanoyl)pyrrolidine- | Homo sapiens | 2 | ALA5042475 | cell-based format | Scientific Literature | |
17. | ALA5042879 | Functional | Antagonist activity at human NPFF1R expressed in CHO cells by GTPgammaS assay | Homo sapiens | 1 | ALA5042475 | cell-based format | Scientific Literature | |
18. | ALA5042880 | Functional | Antagonist activity at human NPFF1R expressed in HEK293 cells upto 10 uM by dynamic mass redistribution assay | Homo sapiens | 1 | ALA5042475 | cell-based format | Scientific Literature | |
19. | ALA5042881 | Functional | Antagonist activity at recombinant human Kiss1 receptor expressed in CHO cells preincubated for 10 mins followed by agonist challenge in presence of probenecid by Fluo-4AM staining based fluorescence assay | Homo sapiens | 2 | ALA5042475 | cell-based format | Scientific Literature | |
20. | ALA5042882 | Binding | Antagonist activity at recombinant human PrRP receptor expressed in CHO cells preincubated for 10 mins followed by agonist challenge in presence of probenecid by Fluo-4AM staining based fluorescence assay | Homo sapiens | 2 | ALA5042475 | cell-based format | Scientific Literature |