# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5029310 | F | Cytotoxicity against human KG-1a cells assessed as cell death incubated for 72 hrs by flow cytometry based Annexin V/7-AAD assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
2. | ALA5029313 | F | Cytotoxicity against human HT-29 cells assessed as cell death incubated for 72 hrs by flow cytometry based Annexin V/7-AAD assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
3. | ALA5029314 | F | Cytotoxicity against human LNCaP cells assessed as cell death incubated for 72 hrs by flow cytometry based Annexin V/7-AAD assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA5029316 | F | Cytotoxicity against human BXPC-3 cells assessed as cell death incubated for 72 hrs by MTS assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
5. | ALA5029317 | F | Cytotoxicity against human MIA PaCa-2 cells assessed as cell death incubated for 72 hrs by MTS assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
6. | ALA5029323 | A | Metabolic stability in cryopreserved human hepatocytes assessed as half life at 1 uM for 60 mins by HPLC-MS/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
7. | ALA5029324 | A | Metabolic stability in cryopreserved human hepatocytes assessed as parent compound remaining at 1 uM for 60 mins by HPLC-MS/MS analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
8. | ALA5029326 | F | Cytotoxicity against human KG-1a cells assessed as reduction in leukemic stem cells fraction >= 0.25 uM measured after 48 hrs by FACS assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA5029335 | A | Prodrug activation assessed as carboxypeptidase Y-mediated metabolite C release measured within 10 mins by NMR analysis | Saccharomyces cerevisiae | 1 | assay format | Scientific Literature | ||
10. | ALA5029336 | A | Prodrug activation assessed as carboxypeptidase Y-mediated metabolite A release measured within 10 mins by NMR analysis | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature |