# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5043203 | B | Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assay | Homo sapiens | 40 | single protein format | Scientific Literature | ||
2. | ALA5043204 | B | Inhibition of BTK phosphorylation in human whole blood assessed as reduction in BTK phosphorylation incubated for 30 mins | Homo sapiens | 17 | tissue-based format | Scientific Literature | ||
3. | ALA5043205 | B | Inhibition of CD69 in human whole blood preincubated for 30 mins followed by anti-human IgD stimulation and measured after 18 to 22 hrs by flow cytometry | Homo sapiens | 27 | tissue-based format | Scientific Literature | ||
4. | ALA5043206 | P | Kinetic aqueous solubility of the compound in pH 6.8 | 16 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA5043208 | A | Clearance in rat liver microsomes assessed as hepatic blood flow | Rattus norvegicus | 13 | microsome format | Scientific Literature | ||
6. | ALA5043209 | A | Clearance in human liver microsomes assessed as hepatic blood flow | Homo sapiens | 13 | microsome format | Scientific Literature | ||
7. | ALA5043210 | A | Protein binding in human plasma assessed as unbound fraction at 2 uM by rapid equilibrium dialysis method | Homo sapiens | 13 | cell-free format | Scientific Literature | ||
8. | ALA5043211 | P | Kinetic solubility of the compound at pH 1.5 by shake flask method | 13 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA5043213 | P | Lipophilicity, logD of the compound at pH 7.6 by shake flask assay | 13 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA5043228 | A | Protein binding in rat plasma assessed as unbound fraction at 2 uM by rapid equilibrium dialysis method | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
11. | ALA5043229 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature | ||
12. | ALA5043230 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 4 | single protein format | Scientific Literature |