# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5035745 | ADME | Cytotoxicity against human wild type CMS-24949 cells in presence of aminoguanidine measured after 72 hrs | Homo sapiens | 3 | ALA5034033 | cell-based format | Scientific Literature | |
2. | ALA5035746 | ADME | Cytotoxicity against SMS mutant human CMS-26559 cells in presence of aminoguanidine measured after 72 hrs | Homo sapiens | 3 | ALA5034033 | cell-based format | Scientific Literature | |
3. | ALA5035747 | ADME | Cytotoxicity against SMS mutant human CMS-6233 cells in presence of aminoguanidine measured after 72 hrs | Homo sapiens | 3 | ALA5034033 | cell-based format | Scientific Literature | |
4. | ALA5035748 | ADME | Cytotoxicity against SMS mutant human CMS-23916 cells in presence of aminoguanidine measured after 72 hrs | Homo sapiens | 3 | ALA5034033 | cell-based format | Scientific Literature | |
5. | ALA5035749 | ADME | Cytotoxicity against SMS mutant human CMS-26559 cells in absence of aminoguanidine measured after 72 hrs | Homo sapiens | 2 | ALA5034033 | cell-based format | Scientific Literature | |
6. | ALA5035750 | Functional | Effect on intracellular putrescine level in SRS patient derived wild type human CMS-24949 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 0.41 +/- 0.1 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
7. | ALA5035751 | Functional | Effect on intracellular putrescine level in SRS patient derived SMS mutant human CMS-26559 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 1.27 +/- 0.40 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
8. | ALA5035752 | Functional | Effect on intracellular putrescine level in SRS patient derived SMS mutant human CMS-6233 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 3.86 +/- 0.68 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
9. | ALA5035753 | Functional | Effect on intracellular putrescine level in SRS patient derived SMS mutant human CMS-23916 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 1.26 +/- 0.24 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
10. | ALA5035754 | Functional | Effect on intracellular spermidine level in SRS patient derived wild type human CMS-24949 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 1.72 +/- 0.13 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
11. | ALA5035755 | Functional | Effect on intracellular spermidine level in SRS patient derived SMS mutant human CMS-26559 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 35.10 +/- 1.04 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
12. | ALA5035756 | Functional | Effect on intracellular spermidine level in SRS patient derived SMS mutant human CMS-6233 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 12.28 +/- 1.14 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
13. | ALA5035757 | Functional | Effect on intracellular spermidine level in SRS patient derived SMS mutant human CMS-23916 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 16.14 +/- 1.69 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
14. | ALA5035758 | Functional | Effect on intracellular spermine level in SRS patient derived wild type human CMS-24949 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 8.65 +/- 0.94 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
15. | ALA5035759 | Functional | Effect on intracellular spermine level in SRS patient derived SMS mutant human CMS-26559 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 0.71 +/- 0.47 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
16. | ALA5035760 | Functional | Effect on intracellular spermine level in SRS patient derived SMS mutant human CMS-6233 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 7 +/- 0.87 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
17. | ALA5035761 | Functional | Effect on intracellular spermine level in SRS patient derived SMS mutant human CMS-23916 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 4.84 +/- 0.64 nmol/mg) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
18. | ALA5035762 | Functional | Effect on intracellular spermidine-spermine ratio in SRS patient derived wild type human CMS-24949 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 0.20 No_unit) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
19. | ALA5035763 | Functional | Effect on intracellular spermidine-spermine ratio in SRS patient derived SMS mutant human CMS-26559 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 49.43 No_unit) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature | |
20. | ALA5035764 | Functional | Effect on intracellular spermidine-spermine ratio in SRS patient derived SMS mutant human CMS-6233 cells at 5 uM in presence of aminoguanidine incubated for 72 hrs by HPLC analysis (Rvb = 1.75 No_unit) | Homo sapiens | 2 | ALA5034033 | tissue-based format | Scientific Literature |