| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5054271 | A | Cytotoxicity against platelets in human PRP assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature | |
| 2. | ALA5054272 | B | Protac activity at VHL/BCL-XL in human RS4-11 cells assessed as decrease in BCL-XL protein level by densitometric analysis | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature | |
| 3. | ALA5054273 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as decrease in BCL-XL protein level by densitometric analysis | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature | |
| 4. | ALA5054274 | B | Protac activity at VHL/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation measured after 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA5053511 | cell-based format | Scientific Literature | |
| 5. | ALA5054275 | F | Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 13 | ALA5053511 | cell-based format | Scientific Literature | |
| 6. | ALA5054276 | F | Cytotoxicity against human MOLT-4 cells assessed as reduction in cell viability measured after 48 hrs by MTS assay | Homo sapiens | 13 | ALA5053511 | cell-based format | Scientific Literature | |
| 7. | ALA5054292 | B | Binding affinity to Halo-tagged VHL/HiBiT-tagged BCL-XL (unknown origin) expressed in HEK293T cells assessed as ternary complex formation at up to 100000 nM measured after 6 hrs by NanoBRET assay | Homo sapiens | 5 | ALA5053511 | cell-based format | Scientific Literature | |
| 8. | ALA5054293 | B | Binding affinity to Halo-tagged VHL/HiBiT-tagged BCL-2 (unknown origin) expressed in HEK293T cells assessed as ternary complex formation at up to 100000 nM measured after 6 hrs by NanoBRET assay | Homo sapiens | 5 | ALA5053511 | cell-based format | Scientific Literature | |
| 9. | ALA5054294 | F | Cytotoxicity against human RS4-11 cells assessed as reduction in cell viability measured after 48 hrs in presence of VHL-032 by MTS assay | Homo sapiens | 4 | ALA5053511 | cell-based format | Scientific Literature | |
| 10. | ALA5054299 | F | Ratio of IC50 for cytotoxicity against human RS4-11 cells in presence of VHL-032 to IC50 for cytotoxicity against human RS4-11 cells | Homo sapiens | 2 | ALA5053511 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!