# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5053781 | B | Agonist activity at RORgammat in mouse CD4+ T cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 production measured after 4 days by intracellular staining based flow cytometry | Mus musculus | 1 | cell-based format | Scientific Literature | ||
2. | ALA5053782 | B | Agonist activity at human RORgammat LBD expressed in HEK293T cells assessed as maximum activation measured after 16 to 20 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
3. | ALA5053783 | B | Agonist activity at human RORgammat LBD expressed in HEK293T cells assessed as increase in Gal4 reporter gene transcription measured after 16 to 20 hrs by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA5053784 | B | Agonist activity at RORgammat in mouse CD4+ T cells assessed as induction of Th17 cells differentiation by measuring increase in IL17 production at 250 nM measured after 4 days by intracellular staining based flow cytometry (Rvb = 16.5 %) | Mus musculus | 1 | cell-based format | Scientific Literature |