| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5030685 | A | Cytotoxicity in human SKNBE2 cells assessed as reduction in cell viability at 0.5 to 5 uM incubated for 18 hrs by Cell Titer-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5030693 | B | Modulation of Gal4-fused VP16 expressed in SKNBE(2) cells co-transfected with UAS repoter gene assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Human alphaherpesvirus 2 | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5030694 | B | Modulation of Gal4-fused VP16 expressed in PC12 cells co-transfected with UAS repoter gene assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Human alphaherpesvirus 2 | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5030695 | B | Modulation of Gal4-fused VP16 expressed in HEK293T cells co-transfected with UAS repoter gene assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Human alphaherpesvirus 2 | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5030730 | B | Modulation of full length human Nurr1 expressed in PC-12 cells co-transfected with RXRalpha and luciferase reporter plasmid harboring NurRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5030731 | B | Modulation of full length human Nurr1 expressed in SKNBE(2) cells co-transfected with RXRalpha and luciferase reporter plasmid harboring NurRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5030732 | B | Modulation of full length human Nurr1 expressed in SKNBE(2) cells co-transfected with luciferase reporter plasmid harboring NurRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5030733 | B | Modulation of full length human Nurr1 expressed in SKNBE(2) cells co-transfected with luciferase reporter plasmid harboring NBRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5030734 | B | Agonist activity at full length NURR1 (unknown origin) expressed in mouse MND9 cells by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5030742 | B | Modulation of full length human Nurr1 expressed in HEK293T cells co-transfected with RXRalpha and luciferase reporter plasmid harboring NurRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5030743 | B | Modulation of full length human Nurr1 expressed in HEK293T cells co-transfected with RXRalpha and luciferase reporter plasmid harboring NBRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5030744 | B | Modulation of full length human Nurr1 expressed in HEK293T cells co-transfected with luciferase reporter plasmid harboring NurRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5030745 | B | Modulation of full length human Nurr1 expressed in HEK293T cells co-transfected with luciferase reporter plasmid harboring NBRE response element assessed as increase in luciferase activity at 0.5 to 5 uM incubated for 18 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5030746 | A | Cytotoxicity in human HEK293T cells assessed as reduction in cell viability at 0.5 to 5 uM incubated for 18 hrs by Cell Titer-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5030754 | B | Binding affinity to recombinant full length N-terminal His-tagged Nurr1 LBD (353 to 598 residue) expressed in Escherichia coli BL21 by NMR spectroscopy analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 16. | ALA5030780 | A | Cytotoxicity in rat PC-12 cells assessed as reduction in cell viability at 0.5 to 5 uM incubated for 18 hrs by Cell Titer-Glo assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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