# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5033582 | F | Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 23 | ALA5032522 | cell-based format | Scientific Literature | |
2. | ALA5033583 | F | Antiproliferative activity against human U-251 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Homo sapiens | 23 | ALA5032522 | cell-based format | Scientific Literature | |
3. | ALA5033584 | F | Antiproliferative activity against rat C6 cells assessed as inhibition of cell growth measured after 72 hrs by CCK-8 assay | Rattus norvegicus | 23 | ALA5032522 | cell-based format | Scientific Literature | |
4. | ALA5033585 | B | Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated 10 mins followed by substrate addition and measured after 2 mins by ELISA | Homo sapiens | 23 | ALA5032522 | single protein format | Scientific Literature | |
5. | ALA5033586 | B | Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA relaxation incubated for 45 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 23 | ALA5032522 | single protein format | Scientific Literature | |
6. | ALA5033587 | B | Inhibition of human topoisomerase I using DNA pBR322 as substrate assessed as DNA intercalation at 100 uM incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis method | Homo sapiens | 4 | ALA5032522 | single protein format | Scientific Literature | |
7. | ALA5033588 | B | Inhibition of human topoisomerase 2 alpha using supercoiled DNA pBR322 as substrate assessed as DNA relaxation at 100 uM incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 2 | ALA5032522 | single protein format | Scientific Literature | |
8. | ALA5033589 | F | Antiproliferative activity against human U-87 MG cells assessed as inhibition of cell growth measured up to 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
9. | ALA5033590 | F | Antiproliferative activity against human U-251 cells assessed as inhibition of cell growth measured up to 72 hrs by CCK-8 assay | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
10. | ALA5033591 | F | Induction of morphological changes in human U-87 MG cells assessed as appearance of rounded and shortened cells at 3.3 uM incubated for 72 hrs by Giemsa staining based light microscopic method | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
11. | ALA5033592 | F | Induction of morphological changes in human U-87 MG cells assessed as appearance of spindle cell shape at 3.3 uM incubated for 72 hrs by Giemsa staining based light microscopic method | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
12. | ALA5033593 | F | Inhibition of colony formation in human U-87 MG cells measured after 8 days by crystal violet staining based assay | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
13. | ALA5033594 | F | Inhibition of colony formation in human U-251 cells measured after 8 days by crystal violet staining based assay | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
14. | ALA5033595 | F | Induction of cell cycle arrest in human U-87 MG cells assessed as accumulation of cells at G2/M phase incubated for 72 hrs by propidium iodide/RNase A staining based flow cytometry analysis | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
15. | ALA5033596 | F | Induction of cell cycle arrest in human U-251 cells assessed as accumulation of cells at G2/M phase incubated for 72 hrs by propidium iodide/RNase A staining based flow cytometry analysis | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
16. | ALA5033597 | F | Induction of cell cycle arrest in human U-251 cells assessed as increase in G2 phase accumulation at 10 uM incubated for 72 hrs by propidium iodide/RNase A staining based flow cytometry (Rvb = 20.88%) | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
17. | ALA5033598 | F | Induction of cell cycle arrest in human U-251 cells assessed as reduction in G0/G1 phase accumulation at 10 uM incubated for 72 hrs by propidium iodide/RNase A staining based flow cytometry (Rvb = 79.12%) | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
18. | ALA5033599 | F | Induction of cell cycle arrest in human U-87 MG assessed as decrease in G0/G1 phase accumulation at 10 uM incubated for 72 hrs by propidium iodide/RNase A staining based flow cytometry | Homo sapiens | 2 | ALA5032522 | cell-based format | Scientific Literature | |
19. | ALA5033600 | F | Inhibition of cell invasion in human U-251 cells incubated for 24 hrs by crystal violet staining based light microscopic analysis | Homo sapiens | 3 | ALA5032522 | cell-based format | Scientific Literature | |
20. | ALA5033601 | F | Inhibition of cell invasion in human U-87 MG cells incubated for 24 hrs by crystal violet staining based light microscopic analysis | Homo sapiens | 3 | ALA5032522 | cell-based format | Scientific Literature |