| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5030469 | B | Antagonist activity at human RXR-alpha expressed in African green monkey COS-1 cells assessed as reduction in NEt-TMN-induced receptor transactivation at 1 uM by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA5030470 | B | Antagonist activity at human RXR-alpha expressed in African green monkey COS-1 cells assessed as reduction in bexarotene-induced receptor transactivation at 1 uM by luciferase reporter gene assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA5030471 | B | Binding affinity to human RXRalpha-LBD expressed in African green monkey COS-1 cells assessed as dissociated constant incubated for 2 hrs by tryptophan fluorescence quenching assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 4. | ALA5030472 | B | Displacement of NEt-C343 from human RXRalpha-LBD expressed in African green monkey COS-1 cells assessed as inhibition constant incubated for 2 hrs by competitive binding assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 5. | ALA5030473 | B | Ratio of Ki for displacement of NEt-C343 from human RXRalpha-LBD expressed in African green monkey COS-1 cells to Kd for binding affinity to human RXRalpha-LBD expressed in African green monkey COS-1 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA5030474 | A | Drug uptake in African green monkey COS-1 cells at 10 uM measured after 24 hrs by trypan blue staining based LC-MS/MS analysis | Chlorocebus aethiops | 4 | tissue-based format | Scientific Literature | ||
| 7. | ALA5030475 | B | Antagonist activity at human RXR-alpha expressed in African green monkey COS-1 cells assessed as reduction in NEt-TMN-induced receptor transactivation by measuring shift in concentration-response curve at 1 uM by luciferase reporter gene assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA5030477 | B | Agonist activity at human RXR-alpha expressed in African green monkey COS-1 cells assessed as NEt-TMN-induced receptor transactivation by luciferase reporter gene assay | Homo sapiens | 4 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!