| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5045272 | B | Inhibition of mouse MAGL using 2-AG as substrate incubated for 30 mins | Mus musculus | 21 | single protein format | Scientific Literature | ||
| 2. | ALA5045273 | P | Distribution coefficient between 1-octanol and phosphate buffer, logD of the compound after 15 mins by shake flask assay | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA5045288 | B | Inhibition of Cynomolgus monkey MAGL using 2-AG as substrate incubated for 30 mins | Macaca fascicularis | 1 | assay format | Scientific Literature | ||
| 4. | ALA5045289 | A | Stability in mouse serum at 37 degC for 2 hrs by UPLC analysis | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 5. | ALA5045290 | A | Stability in human serum at 37 degC for 2 hrs by UPLC analysis | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 6. | ALA5045291 | B | Inhibition of human MAGL using 2-AG as substrate incubated for 30 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 7. | ALA5045292 | A | Protein binding in human plasma assessed as free plasma concentration incubated for 10 mins by ultracentrifugation | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 8. | ALA5045293 | A | Protein binding in mouse plasma assessed as free plasma concentration incubated for 10 mins by ultracentrifugation | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 9. | ALA5045294 | A | Ex vivo biodistribution in C57BL/6 mouse spleen at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA5045295 | A | Ex vivo biodistribution in C57BL/6 mouse liver at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA5045296 | A | Ex vivo biodistribution in C57BL/6 mouse kidney at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5045297 | A | Ex vivo biodistribution in C57BL/6 mouse lung at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5045298 | A | Ex vivo biodistribution in C57BL/6 mouse bone at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA5045299 | A | Ex vivo biodistribution in C57BL/6 mouse heart at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5045300 | A | Ex vivo biodistribution in C57BL/6 mouse brain at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5045301 | A | Ex vivo biodistribution in C57BL/6 mouse Gall bladder at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5045302 | A | Ex vivo biodistribution in C57BL/6 mouse blood at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA5045303 | A | Ex vivo biodistribution in C57BL/6 mouse urine at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5045304 | A | Ex vivo biodistribution in C57BL/6 mouse White adipose tissue at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA5045305 | A | Ex vivo biodistribution in C57BL/6 mouse Brown adipose tissue at 16.50 to 17.59 MBq, iv preincubated in presence of PF-06795071 followed by compound addition for 30 mins by gamma counter method | Mus musculus | 1 | organism-based format | Scientific Literature |
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