# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5041511 | Binding | Protac activity at CRBN/PDE6D in human MOLT-4 cells assessed as induction of PDE6D degradation at 200 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
2. | ALA5041513 | Binding | Protac activity at CRBN/IKZF3 in human MOLT-4 cells assessed as induction of IKZF3 degradation at 200 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
3. | ALA5041514 | Binding | Induction of PDE6D degradation in human CRBN-null MOLT4 cells at 8 to 200 nM incubated for 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
4. | ALA5041515 | Binding | Protac activity at CRBN/IKZF1 in human MOLT-4 cells assessed as induction of IKZF1 degradation at 200 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
5. | ALA5041516 | Binding | Protac activity at CRBN/PDE6D in human MOLT-4 cells assessed as induction of PDE6D degradation at 1 uM measured upto 24 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
6. | ALA5041517 | Binding | Protac activity at CRBN/PDE6D in human MOLT-4 cells assessed as induction of PDE6D degradation at 8 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
7. | ALA5041518 | Binding | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 200 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
8. | ALA5041536 | Functional | Antiproliferative activity against human MIA PaCa-2 cells assessed as reduction in cell viability measured after 3 days by Celltiter-Glo assay | Homo sapiens | 5 | ALA5038641 | cell-based format | Scientific Literature | |
9. | ALA5041537 | Functional | Antiproliferative activity against human AGS cells assessed as reduction in cell viability measured after 3 days by Celltiter-Glo assay | Homo sapiens | 5 | ALA5038641 | cell-based format | Scientific Literature | |
10. | ALA5041538 | Functional | Antiproliferative activity against human NCI-H358 cells assessed as reduction in cell viability measured after 3 days by Celltiter-Glo assay | Homo sapiens | 5 | ALA5038641 | cell-based format | Scientific Literature | |
11. | ALA5041539 | Functional | Antiproliferative activity against human PaTu 8988t cells assessed as reduction in cell viability measured after 3 days by Celltiter-Glo assay | Homo sapiens | 5 | ALA5038641 | cell-based format | Scientific Literature | |
12. | ALA5041540 | Binding | Induction of IKZF1 degradation in human CRBN-null MOLT4 cells at 8 to 200 nM incubated for 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
13. | ALA5041541 | Binding | Protac activity at CRBN/PDE6D in human MOLT-4 cells assessed as induction of PDE6D degradation at 1 uM measured after 5 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
14. | ALA5041542 | Binding | Protac activity at CRBN/IKZF1 in human MOLT-4 cells assessed as induction of IKZF1 degradation at 1 microM measured after 5 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
15. | ALA5041543 | Binding | Protac activity at CRBN/IKZF3 in human MOLT-4 cells assessed as induction of IKZF3 degradation at 1 microM measured after 5 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
16. | ALA5041544 | Binding | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 1 microM measured after 5 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature |