# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5042071 | F | Antiproliferative activity against human ML-1 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 6 | ALA5038665 | cell-based format | Scientific Literature | |
2. | ALA5042073 | F | Antiproliferative activity against human HL-60 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 6 | ALA5038665 | cell-based format | Scientific Literature | |
3. | ALA5042074 | T | Antiproliferative activity against mouse BaF3 cells expressing wild type FLT3 assessed as reduction in cell viability measured after 72 hrs by MTS assay | Mus musculus | 4 | ALA5038665 | cell-based format | Scientific Literature | |
4. | ALA5042075 | F | Antiproliferative activity against human MOLM-13 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs by MTS assay | Homo sapiens | 4 | ALA5038665 | cell-based format | Scientific Literature | |
5. | ALA5042076 | F | Antiproliferative activity against mouse Ba/F3 FLT3-ITD cells assessed as reduction in cell viability measured after 72 hrs by MTS assay | Mus musculus | 4 | ALA5038665 | cell-based format | Scientific Literature | |
6. | ALA5042077 | F | Antiproliferative activity against human MV4-11 cells harboring FLT3-ITD mutant assessed as reduction in cell viability measured after 72 hrs ny MTS assay | Homo sapiens | 4 | ALA5038665 | cell-based format | Scientific Literature | |
7. | ALA5042078 | B | Inhibition of BRAF (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
8. | ALA5042079 | B | Inhibition of FGFR1 (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
9. | ALA5042080 | P | Water solubility of compound at pH 1.2 | 4 | ALA5038665 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA5042081 | B | Inhibition of VEGFR1 (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
11. | ALA5042082 | B | Inhibition of KIT (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
12. | ALA5042083 | P | Water solubility of compound at pH 6.8 | 4 | ALA5038665 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA5042084 | B | Inhibition of FLT3 (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
14. | ALA5042085 | B | Inhibition of FLT3-ITD mutant (unknown origin) | Homo sapiens | 2 | ALA5038665 | single protein format | Scientific Literature | |
15. | ALA5042095 | B | Inhibition of FLT3 phosphorylation in human MV4-11 cells assessed as reduction in phosphorylated FLT3 level measured after 12 hrs by western blot analysis | Homo sapiens | 2 | ALA5038665 | cell-based format | Scientific Literature | |
16. | ALA5042096 | B | Inhibition of FLT3 phosphorylation in mouse Ba/F3 FLT3-ITD cells assessed as reduction in phosphorylated FLT3 level measured after 12 hrs by western blot analysis | Mus musculus | 2 | ALA5038665 | cell-based format | Scientific Literature | |
17. | ALA5042099 | T | Antiproliferative activity against human peripheral blood monocyte cells assessed as cell growth inhibition at 6 to 200 uM measured after 72 hrs by MTS assay | Homo sapiens | 1 | ALA5038665 | cell-based format | Scientific Literature | |
18. | ALA5042100 | B | Inhibition of FLT3 phosphorylation in mouse Ba/F3 FLT3-ITD cells assessed as reduction in phosphorylated FLT3 level at 0.3 to 100 nM by sandwich ELISA assay | Mus musculus | 1 | ALA5038665 | cell-based format | Scientific Literature | |
19. | ALA5042101 | B | Inhibition of FLT3 phosphorylation in human MOLM-13 cells assessed as reduction in phosphorylated FLT3 level at 0.3 to 100 nM by sandwich ELISA assay | Homo sapiens | 1 | ALA5038665 | cell-based format | Scientific Literature | |
20. | ALA5042102 | B | Inhibition of FLT3 phosphorylation in human MV4-11 cells assessed as reduction in phosphorylated FLT3 level at 0.3 to 100 nM by sandwich ELISA assay | Homo sapiens | 1 | ALA5038665 | cell-based format | Scientific Literature |