# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5056431 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA5055640 | cell-based format | Scientific Literature | |
2. | ALA5056432 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA5055640 | cell-based format | Scientific Literature | |
3. | ALA5056433 | F | Antiproliferative activity against human A549 cells assessed as reduction in cell viability at 1 uM incubated for 48 hrs by MTT assay | Homo sapiens | 6 | ALA5055640 | cell-based format | Scientific Literature | |
4. | ALA5056434 | F | Antiproliferative activity against human A172 cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA5055640 | cell-based format | Scientific Literature | |
5. | ALA5056435 | F | Antiproliferative activity against human A172 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA5055640 | cell-based format | Scientific Literature | |
6. | ALA5056436 | F | Antiproliferative activity against human A172 cells assessed as reduction in cell viability at 1 uM incubated for 48 hrs by MTT assay | Homo sapiens | 8 | ALA5055640 | cell-based format | Scientific Literature | |
7. | ALA5056437 | F | Antiproliferative activity against human U-87MG cells assessed as reduction in cell viability at 50 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 5 | ALA5055640 | cell-based format | Scientific Literature | |
8. | ALA5056438 | F | Antiproliferative activity against human U-87MG cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 5 | ALA5055640 | cell-based format | Scientific Literature | |
9. | ALA5056439 | F | Antiproliferative activity against human U-87MG cells assessed as reduction in cell viability at 1 uM incubated for 48 hrs by MTT assay relative to control | Homo sapiens | 5 | ALA5055640 | cell-based format | Scientific Literature | |
10. | ALA5056441 | B | Inhibition of human ERG at 1 uM relative to control | Homo sapiens | 1 | ALA5055640 | single protein format | Scientific Literature | |
11. | ALA5056442 | A | Inhibition of CYP2D6 (unknown origin) using quinidine as substrate | Homo sapiens | 2 | ALA5055640 | single protein format | Scientific Literature | |
12. | ALA5056443 | A | Inhibition of CYP3A4 (unknown origin) using ketoconazole as substrate | Homo sapiens | 2 | ALA5055640 | single protein format | Scientific Literature | |
13. | ALA5056444 | A | Microsomal stability in human liver microsome assessed as half life at 0.1 mg/ml | Homo sapiens | 2 | ALA5055640 | microsome format | Scientific Literature | |
14. | ALA5056445 | A | Microsomal stability in human liver microsome assessed as intrinsic clearance at 0.1 mg/ml incubated upto 1 hour | Homo sapiens | 2 | ALA5055640 | microsome format | Scientific Literature | |
15. | ALA5056446 | A | Apparent permeability across basolateral to apical side in human Caco2 cells at 10 uM | Homo sapiens | 2 | ALA5055640 | cell-based format | Scientific Literature | |
16. | ALA5056447 | A | Apparent permeability across apical to basolateral side in human Caco2 cells at 10 uM | Homo sapiens | 2 | ALA5055640 | cell-based format | Scientific Literature | |
17. | ALA5056448 | P | Aqueous solubility of the compound in simulated gastric fluid | 1 | ALA5055640 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA5056449 | B | Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometry | Rattus norvegicus | 24 | ALA5055640 | microsome format | Scientific Literature | |
19. | ALA5056450 | B | Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometry | Rattus norvegicus | 24 | ALA5055640 | microsome format | Scientific Literature | |
20. | ALA5056451 | F | Antiinvasive activity against human U-87 MG cells assessed as reduction in cell motility measured after 48 hrs by wound healing assay | Homo sapiens | 1 | ALA5055640 | cell-based format | Scientific Literature |