# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA851081 | ADME | Therapeutic Index measured as the ratio of CyD50(polio) / ED99(polio) values | Human enterovirus C | 38 | ALA1125251 | organism-based format | Scientific Literature | |
2. | ALA851082 | ADME | Therapeutic Index measured as the ratio of CyD50 (rhino) / ED99 (rhino) values. | 18 | ALA1125251 | assay format | Scientific Literature | ||
3. | ALA1073434 | Binding | Inhibition of Spanish flu (A/Bervig_Mission/1/18) neuraminidase | Influenza A virus (A/Brevig Mission/1/1918(H1N1)) | 13 | ALA1156844 | assay format | Scientific Literature | |
4. | ALA1073435 | Binding | Inhibition of Spanish flu (A/Bervig_Mission/1/18) neuraminidase by noncompetitive inhibition assay | Influenza A virus (A/Brevig Mission/1/1918(H1N1)) | 18 | ALA1156844 | assay format | Scientific Literature | |
5. | ALA3412087 | ADME | Cytotoxicity against rat L6 cells assessed as viable cells at 10 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
6. | ALA3412088 | ADME | Cytotoxicity against rat L6 cells assessed as viable cells at 1 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
7. | ALA3412089 | ADME | Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay | Mus musculus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
8. | ALA3412090 | Functional | Antivascular activity in human EAhy926 cells assessed as concentration require to adopt rounding shape after 2 hrs by microscopic analysis | Homo sapiens | 17 | ALA3407434 | cell-based format | Scientific Literature | |
9. | ALA3412093 | Functional | Leishmanicidal activity against promastigote stage of Leishmania amazonensis MHOM/BR/PH8 after 48 hrs by MTT assay | Leishmania amazonensis | 17 | ALA3407434 | organism-based format | Scientific Literature | |
10. | ALA3412094 | Functional | Antiplasmodial activity against Plasmodium falciparum FcB1/Columbia infected in human red blood cells assessed as parasite growth inhibition at 10 uM after 48 hrs by [3H]-hypoxanthine incorporation assay relative to control | Plasmodium falciparum | 16 | ALA3407434 | organism-based format | Scientific Literature | |
11. | ALA3412096 | Functional | Antitrypanosomal activity against Trypanosoma brucei gambiense Feo assessed as parasite growth inhibition at 50 uM after 72 hrs by fluorescence assay relative to control | Trypanosoma brucei gambiense | 16 | ALA3407434 | organism-based format | Scientific Literature | |
12. | ALA3412097 | Functional | Antitrypanosomal activity against Trypanosoma brucei gambiense Feo assessed as parasite growth inhibition at 10 uM after 72 hrs by fluorescence assay relative to control | Trypanosoma brucei gambiense | 16 | ALA3407434 | organism-based format | Scientific Literature | |
13. | ALA769455 | ADME | Cytotoxic dose at which 50% growth of normal cells is inhibited | Chlorocebus sabaeus | 47 | ALA1125251 | cell-based format | Scientific Literature | |
14. | ALA768385 | Functional | Minimum drug concentration at which 99% of the polio virus is inhibited | Human enterovirus C | 39 | ALA1125251 | organism-based format | Scientific Literature | |
15. | ALA768389 | Functional | Maximal non-toxic dose (MNTD) that shows antiviral activity. | Human enterovirus C | 61 | ALA1125251 | organism-based format | Scientific Literature | |
16. | ALA766871 | Functional | The ratio of the poliovirus viral titer of the virus control (reduction factor) to the viral titer in the presence of the maximal non-toxic dose (RF MNTD) | Human enterovirus C | 48 | ALA1125251 | organism-based format | Scientific Literature | |
17. | ALA766876 | Functional | Minimal dose which produces titer reduction at 10 ug/mL (mD RF10e3) | Human enterovirus C | 35 | ALA1125251 | organism-based format | Scientific Literature | |
18. | ALA882153 | Functional | Cytotoxic dose at which 50% growth of normal cells is inhibited against rhino virus infection. | Human rhinovirus sp. | 28 | ALA1125251 | organism-based format | Scientific Literature | |
19. | ALA799318 | Functional | Minimum drug concentration at which 99% of the rhino virus is inhibited. | Human rhinovirus sp. | 23 | ALA1125251 | organism-based format | Scientific Literature | |
20. | ALA930438 | Functional | Antiinflammatory activity in human neutrophils assessed as inhibition of fMet-Leu-Phe/Cytochalasin B-induced superoxide anion generation | Homo sapiens | 8 | ALA1143073 | cell-based format | Scientific Literature |