| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3507681 | Toxicity | Human HepG2 cell viability assay in 384 well format | Homo sapiens | 68,614 | ALA3507680 | cell-based format | Gates Library compound collection | |
| 2. | ALA851081 | ADME | Therapeutic Index measured as the ratio of CyD50(polio) / ED99(polio) values | Human enterovirus C | 38 | ALA1125251 | organism-based format | Scientific Literature | |
| 3. | ALA1794345 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 4. | ALA1794401 | Functional | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | 91,504 | ALA1201862 | assay format | PubChem BioAssays | ||
| 5. | ALA1794433 | Functional | PUBCHEM_BIOASSAY: Confirmation qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) - Round 2 Cherry Picks. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2367, AID593, AID594] | 543 | ALA1201862 | assay format | PubChem BioAssays | ||
| 6. | ALA1794483 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | 114,923 | ALA1201862 | assay format | PubChem BioAssays | ||
| 7. | ALA1794486 | Functional | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] | 10,834 | ALA1201862 | assay format | PubChem BioAssays | ||
| 8. | ALA1794512 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Cell Surface uPA Generation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493178] | 12,416 | ALA1201862 | assay format | PubChem BioAssays | ||
| 9. | ALA1794536 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | 7,413 | ALA1201862 | assay format | PubChem BioAssays | ||
| 10. | ALA1794557 | Binding | PUBCHEM_BIOASSAY: MLPCN Dyrk1A Kinase Measured in Biochemical System Using Plate Reader - 2124-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504442] | Homo sapiens | 854 | ALA1201862 | biochemical format | PubChem BioAssays | |
| 11. | ALA1794569 | Functional | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] | 18,965 | ALA1201862 | assay format | PubChem BioAssays | ||
| 12. | ALA1794580 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 130,890 | ALA1201862 | organism-based format | PubChem BioAssays | |
| 13. | ALA3412087 | ADME | Cytotoxicity against rat L6 cells assessed as viable cells at 10 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
| 14. | ALA3412088 | ADME | Cytotoxicity against rat L6 cells assessed as viable cells at 1 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
| 15. | ALA3412089 | ADME | Cytotoxicity against mouse B16 cells assessed as cell viability after 48 hrs by MTT assay | Mus musculus | 16 | ALA3407434 | cell-based format | Scientific Literature | |
| 16. | ALA3412090 | Functional | Antivascular activity in human EAhy926 cells assessed as concentration require to adopt rounding shape after 2 hrs by microscopic analysis | Homo sapiens | 17 | ALA3407434 | cell-based format | Scientific Literature | |
| 17. | ALA3412093 | Functional | Leishmanicidal activity against promastigote stage of Leishmania amazonensis MHOM/BR/PH8 after 48 hrs by MTT assay | Leishmania amazonensis | 17 | ALA3407434 | organism-based format | Scientific Literature | |
| 18. | ALA3412094 | Functional | Antiplasmodial activity against Plasmodium falciparum FcB1/Columbia infected in human red blood cells assessed as parasite growth inhibition at 10 uM after 48 hrs by [3H]-hypoxanthine incorporation assay relative to control | Plasmodium falciparum | 16 | ALA3407434 | organism-based format | Scientific Literature | |
| 19. | ALA3412096 | Functional | Antitrypanosomal activity against Trypanosoma brucei gambiense Feo assessed as parasite growth inhibition at 50 uM after 72 hrs by fluorescence assay relative to control | Trypanosoma brucei gambiense | 16 | ALA3407434 | organism-based format | Scientific Literature | |
| 20. | ALA3412097 | Functional | Antitrypanosomal activity against Trypanosoma brucei gambiense Feo assessed as parasite growth inhibition at 10 uM after 72 hrs by fluorescence assay relative to control | Trypanosoma brucei gambiense | 16 | ALA3407434 | organism-based format | Scientific Literature |
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