| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5033516 | B | Binding affinity to eGFP-fused human TEAD2 (217 to 447 residues) expressed in CHO-K1 cells by microscale thermophoresis analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA5033517 | B | Inhibition of TEAD (unknown origin) transfected in HEK293T cells assessed as inhibition of TEAD transcriptional activity at 10 uM measured after 16 hrs by luciferase reporter gene assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA5033518 | B | Inhibition of TEAD (unknown origin) transfected in HEK293T cells assessed as inhibition of TEAD transcriptional activity measured after 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5033519 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in AXL protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5033520 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in CTGF protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5033521 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in Cyr61 protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5033522 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in Survivin protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5033523 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in AXL mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5033524 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in CTGF mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5033525 | B | Inhibition of YAP/TAZ-TEAD interaction in human MDA-MB-231 cells assessed as reduction in Cyr61 mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5033526 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation at 5 uM measured after 48 hrs by IncuCyte live-cell imaging assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5033527 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell proliferation at 10 uM measured after 48 hrs by IncuCyte live-cell imaging assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5033533 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in AXL protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA5033534 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in CTGF protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5033535 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in Cyr61 protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5033536 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in Survivin protein expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5033537 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in AXL mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5033538 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in CTGF mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5033539 | B | Inhibition of YAP/TAZ-TEAD interaction in human HeLa cells assessed as reduction in Cyr61 mRNA expression at 10 uM measured after 24 hrs by qRT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5033540 | F | Effect on AXL protein expression in human SH-SY5Y cells lacking YAP/TAZ expression at 10 uM measured after 48 hrs by western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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