| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5045649 | Binding | Inhibition of GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone H4 peptides as substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 23 | ALA5042544 | assay format | Scientific Literature | |
| 2. | ALA5045652 | Binding | Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone H4 peptides as substrate incubated for 30 mins by TR-FRET assay | Homo sapiens | 22 | ALA5042544 | assay format | Scientific Literature | |
| 3. | ALA5045653 | Binding | Inhibition of GST-ATAD2 BD (951 to 1132 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) and biotinylated tetra-acetylated histone H4 peptides as substrate by TR-FRET artifact assay | Homo sapiens | 21 | ALA5042544 | assay format | Scientific Literature | |
| 4. | ALA5045654 | Binding | Displacement of Alexafluor 647-JQ1 from GST-BRD4 BD1 BD2 (44 to 460 residues) (unknown origin) incubated for 60 mins by fluorescence polarization assay | Homo sapiens | 20 | ALA5042544 | single protein format | Scientific Literature | |
| 5. | ALA5045655 | Physicochemical | Distribution coefficient, logD of compound at pH 7.4 | 23 | ALA5042544 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA5045656 | Binding | Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2A BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated for 18 hrs by NanoBRET assay | Homo sapiens | 7 | ALA5042544 | cell-based format | Scientific Literature | |
| 7. | ALA5045657 | Binding | Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated for 18 hrs in presence of efflux inhibitor reversan by NanoBRET assay | Homo sapiens | 4 | ALA5042544 | cell-based format | Scientific Literature | |
| 8. | ALA5045658 | Binding | Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated for 18 hrs in presence of efflux inhibitor verapamil by NanoBRET assay | Homo sapiens | 4 | ALA5042544 | cell-based format | Scientific Literature | |
| 9. | ALA5045659 | Binding | Displacement of Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (962 to 1119 residues) (unknown origin) transfected in human HCT116 cells incubated for 18 hrs in presence of efflux inhibitor elacridar by NanoBRET assay | Homo sapiens | 4 | ALA5042544 | cell-based format | Scientific Literature | |
| 10. | ALA5045660 | Binding | Displacement of Halo-tagged Histone H3.3 from Nanoluc-BRD4 BD1/BD2 (44 to 460 residues) (unknown origin) transfected in human HCT116 cells incubated for 18 hrs by NanoBRET assay | Homo sapiens | 6 | ALA5042544 | cell-based format | Scientific Literature | |
| 11. | ALA5045709 | Binding | Selectivity ratio of IC50 for Inhibition of full length GST-ATAD2 BD (981 to 1108 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) to IC50 for Halo-tagged Histone H3.3 from Nanoluc-ATAD2 BD (951 to 1132 residues) (unknown origin) transfected in human HCT116 cells | Homo sapiens | 7 | ALA5042544 | cell-based format | Scientific Literature |
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