| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5034632 | B | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA5034633 | B | Inhibition of human alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA5034634 | B | Inhibition of human alpha2beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA5034635 | B | Inhibition of human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA5034636 | B | Inhibition of human alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA5034637 | B | Inhibition of human alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA5034638 | B | Inhibition of human alpha4beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA5034639 | B | Inhibition of human alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA5034640 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA5034641 | B | Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-electrode voltage-clamp method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA5034642 | F | Antiallodynic activity in oxaliplatin-induced peripheral neuropathy pain CBA/CaJ mouse model assessed as increase in paw withdrawal latency at 40 ug/kg, ip administered once per week and measured after 24 hrs post last dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5034643 | F | Antiallodynic activity in wild type CBA/CaJ mouse model of oxaliplatin-induced peripheral neuropathic pain assessed as reversal of acute cold allodynia at 40 ug/kg, sc measured after 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA5034644 | F | Antiallodynic activity in oxaliplatin-induced peripheral neuropathy pain CBA/CaJ mouse model at 40 ug/kg, ip administered as repeated dose once per week and measured after 24 hrs post last dose | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA5034645 | F | Antiallodynic activity in alpha9 knock out CBA/CaJ mouse model of oxaliplatin-induced peripheral neuropathic pain assessed as reversal of acute cold allodynia at 40 ug/kg, sc measured after 5 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5034646 | A | Stability of the compound in human serum assessed as parent compound remaining measured after 24 hrs by RP-HPLC analysis | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 16. | ALA5034648 | B | Displacement of [3H]-DPCPX from human recombinant adenosine A1 receptor at 10 uM after 60 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA5034649 | B | Displacement of [3H]-CGS 21680 from human recombinant adenosine A2A receptor at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA5034650 | B | Displacement of [3H]- CPX from adenosine A2B receptor (unknown origin) at 10 uM by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 19. | ALA5034651 | B | Displacement of [125I]AB-MECA from human recombinant adenosine A3 receptor at 10 uM after 120 mins by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 20. | ALA5034652 | B | Displacement of [3H]-prazosin from adrenergic alpha1A receptor (unknown origin) at 10 uM by scintillation counting analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!