| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5034987 | B | Binding affinity to full length human Bcl-2 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed by 5-FAM-QEDIIIINIARHLAQVGDSMD-RSIPPG tracer addition and measured after 20 mins by fluorescence polarization assay | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 2. | ALA5034988 | B | Binding affinity to full length human MCL1 expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant preincubated for 30 mins followed by 5-FAM-QEDIIIINIARHLAQVGDSMD-RSIPPG tracer addition and measured after 20 mins by fluorescence polarization assay | Homo sapiens | 31 | assay format | Scientific Literature | ||
| 3. | ALA5034989 | F | Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK8 assay | Homo sapiens | 87 | cell-based format | Scientific Literature | ||
| 4. | ALA5034990 | F | Cytotoxicity against human HL-60 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK8 assay | Homo sapiens | 88 | cell-based format | Scientific Literature | ||
| 5. | ALA5034992 | F | Cytotoxicity against human RS4-11 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK8 assay | Homo sapiens | 90 | cell-based format | Scientific Literature | ||
| 6. | ALA5034993 | A | Cytotoxicity against HEK293T cells assessed as reduction in cell viability incubated for 48 hrs by CCK8 assay | Homo sapiens | 86 | cell-based format | Scientific Literature | ||
| 7. | ALA5035013 | B | Binding affinity to full length human Bcl-xl expressed in Escherichia coli BL21 (DE3) at up to 100 uM preincubated for 30 mins followed by 5-FAM-QEDIIIINIARHLAQVGDSMD-RSIPPG tracer addition and measured after 20 mins by fluorescence polarization assay | Homo sapiens | 65 | assay format | Scientific Literature | ||
| 8. | ALA5113841 | B | Binding affinity to Mcl-1 (unknown origin) assessed as inhibition constant by fluorescence polarization assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 9. | ALA5113891 | B | Binding affinity to Bcl-2/Bid (unknown origin) by fluorescence polarization assay | Homo sapiens | 6 | protein format | Scientific Literature | ||
| 10. | ALA5113897 | B | Binding affinity to Mcl-1/Bid (unknown origin) by fluorescence polarization assay | Homo sapiens | 5 | protein format | Scientific Literature |
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