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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5054067 B Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days followed by replacement with fresh medium containing compound and measured after 3 days by QuantiGene assay Hepatitis B virus 36 ALA5053507 cell-based format Scientific Literature 2. ALA5054068 A Metabolic stability in human liver microsomes assessed as intrinsic clearance Homo sapiens 22 ALA5053507 microsome format Scientific Literature 3. ALA5054069 P Thermodynamic solubility of the compound at pH 7 12 ALA5053507 small-molecule physicochemical format Scientific Literature 4. ALA5054076 A Plasma clearance in Sprague-Dawley rat at 5 mg/kg, po or 1.25 mg/kg, iv Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 5. ALA5054077 A Plasma clearance in CD1 mouse at 10 mg/kg, po or 2.5 mg/kg, iv Mus musculus 1 ALA5053507 organism-based format Scientific Literature 6. ALA5054078 A Plasma clearance in Mongrel dog at 2.5 mg/kg, po or 1 mg/kg, iv Canis lupus familiaris 2 ALA5053507 organism-based format Scientific Literature 7. ALA5054079 A Clearance in Sprague-Dawley rat at 5 mg/kg, po or 1.25 mg/kg, iv relative to liver blood flow Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 8. ALA5054080 A Clearance in CD1 mouse at 10 mg/kg, po or 2.5 mg/kg, iv relative to liver blood flow Mus musculus 1 ALA5053507 organism-based format Scientific Literature 9. ALA5054081 A Clearance in Mongrel dog at 2.5 mg/kg, po or 1 mg/kg, iv relative to liver blood flow Canis lupus familiaris 2 ALA5053507 organism-based format Scientific Literature 10. ALA5054082 A Volume of distribution at steady state in Sprague-Dawley rat at 5 mg/kg, po or 1.25 mg/kg, iv Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 11. ALA5054083 A Volume of distribution at steady state in CD1 mouse at 10 mg/kg, po or 2.5 mg/kg, iv Mus musculus 1 ALA5053507 organism-based format Scientific Literature 12. ALA5054084 A Volume of distribution at steady state in Mongrel dog at 2.5 mg/kg, po or 1 mg/kg, iv Canis lupus familiaris 2 ALA5053507 organism-based format Scientific Literature 13. ALA5054085 A Half life in Sprague-Dawley rat at 5 mg/kg, po or 1.25 mg/kg, iv Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 14. ALA5054086 A Half life in CD1 mouse at 10 mg/kg, po or 2.5 mg/kg, iv Mus musculus 1 ALA5053507 organism-based format Scientific Literature 15. ALA5054087 A Half life in Mongrel dog at 2.5 mg/kg, po or 1 mg/kg, iv Canis lupus familiaris 2 ALA5053507 organism-based format Scientific Literature 16. ALA5054088 A Cmax in Sprague-Dawley rat at 5 mg/kg, po Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 17. ALA5054089 A Cmax in CD1 mouse at 10 mg/kg, po Mus musculus 1 ALA5053507 organism-based format Scientific Literature 18. ALA5054090 A Cmax in Mongrel dog at 2.5 mg/kg, po Canis lupus familiaris 2 ALA5053507 organism-based format Scientific Literature 19. ALA5054091 A Tmax in Sprague-Dawley rat at 5 mg/kg, po Rattus norvegicus 2 ALA5053507 organism-based format Scientific Literature 20. ALA5054092 A Tmax in CD1 mouse at 10 mg/kg, po Mus musculus 1 ALA5053507 organism-based format Scientific Literature