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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA5057980 A AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 2. ALA5057981 F Cytotoxicity against human HT-29 cells assessed as reduction in cell viability by CCK8 assay Homo sapiens 3 cell-based format Scientific Literature 3. ALA5057982 A AUC (0 to t) in Sprague-Dawley rat at 5 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 4. ALA5057983 B Inhibition of IDO1 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based assay Homo sapiens 16 single protein format Scientific Literature 5. ALA5057984 B Inhibition of IDO2 (unknown origin) assessed as reduction in kynurenine formation using L-tryptophan as substrate by methylene blue reagent based assay Homo sapiens 15 single protein format Scientific Literature 6. ALA5057987 B Inhibition of IDO1 in IFNgamma-stimulated human HeLa cells assessed as reduction in kynurenine formation measured after 48 hrs by spectrophotometry Homo sapiens 24 tissue-based format Scientific Literature 7. ALA5057988 B Inhibition of IDO1/IDO2 in IFNgamma/LPS-stimulated human PBMCs assessed as reduction in kynurenine formation at 0.0001 to 10 uM pretreated with compound for 15 mins followed by IFNgamma/LPS stimulation by LC-MS/MS analysis Homo sapiens 2 tissue-based format Scientific Literature 8. ALA5057989 F Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 1 to 10 uM by CCK8 assay Homo sapiens 2 cell-based format Scientific Literature 9. ALA5057990 F Cytotoxicity against mouse CT26 cells assessed as reduction in cell viability by CCK8 assay Mus musculus 3 cell-based format Scientific Literature 10. ALA5057991 F Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability by CCK8 assay Homo sapiens 3 cell-based format Scientific Literature 11. ALA5057992 A Half life in Sprague-Dawley rat at 5 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA5057993 A Volume of distribution at steady state in Sprague-Dawley rat at 5 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 13. ALA5057994 A Clearance in Sprague-Dawley rat at 5 mg/kg, iv Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA5057995 A AUC (0 to t) in Sprague-Dawley rat at 50 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 15. ALA5057996 A AUC (0 to infinity) in Sprague-Dawley rat at 50 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 16. ALA5057997 A Cmax in Sprague-Dawley rat at 50 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 17. ALA5057998 A Tmax in Sprague-Dawley rat at 50 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 18. ALA5057999 A Half life in Sprague-Dawley rat at 50 mg/kg, po Rattus norvegicus 2 organism-based format Scientific Literature 19. ALA5058000 A Oral bioavailability in Sprague-Dawley rat at 50 mg/kg Rattus norvegicus 2 organism-based format Scientific Literature 20. ALA5058001 A Metabolic stability in human liver microsomes assessed as rate constant Homo sapiens 2 microsome format Scientific Literature