| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5055737 | F | Antagonist activity at mouse Neuropeptide S receptor expressed in HEK293 cells assessed as inhibition of NPS stimulated calcium mobilization at 10 mM treated for 24 mins prior to NPS addition measured immediately by Fluo-4AM dye based FLIPR assay | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 2. | ALA5055739 | F | Antagonist activity at mouse Neuropeptide S receptor expressed in HEK293 cells assessed as rightward shift in NPS concentration response curve of intracellular calcium mobilization without affecting maximal effect at 100 nM treated for 24 mins prior to NPS addition measured immediately by Fluo-4AM dye based FLIPR assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA5055741 | A | Effect on locomotor activity in CD-1 mouse at 50 mg/kg, ip measured over 30 mins | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 4. | ALA5055742 | A | Effect on locomotor activity in CD-1 mouse at 10 mg/kg, ip measured over 30 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA5055744 | F | In vivo antagonist activity at neuropeptide S receptor in CD-1 mouse assessed as decrease in NPS-stimulated locomotor activity at 10 mg/kg, ip administered 30 mins prior to NPS stimulation and measured after 15 mins | Mus musculus | 1 | organism-based format | Scientific Literature |
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