#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA5039968	B	Protac activity at VHL/EGFR in human NCI-H1299 cells assessed as induction of EGFR degradation at up to 15 uM incubated for 36 hrs by Western blot analysis	Homo sapiens	8	ALA5038593	cell-based format	Scientific Literature
2.	ALA5039975	B	Protac activity at VHL/PARP-1 in human NCI-H1299 cells assessed as induction of PARP degradation at up to 15 uM incubated for 36 hrs by Western blot analysis	Homo sapiens	8	ALA5038593	cell-based format	Scientific Literature
3.	ALA5039976	B	Protac activity at VHL/PARP-1 in human NCI-H1299 cells assessed as induction of EGFR degradation at 0.47 uM incubated for 36 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
4.	ALA5039977	B	Protac activity at VHL/EGFR in human NCI-H1299 cells assessed as induction of EGFR degradation by measuring reduction in p-EGFR level at 15 uM incubated for 36 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
5.	ALA5039978	B	Protac activity at VHL/PARP-1 in human A-431 cells assessed as induction of PARP-1 degradation at 0.8 to 20 uM incubated for 36 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
6.	ALA5039979	B	Protac activity at VHL/EGFR in human A-431 cells assessed as induction of EGFR degradation at 0.8 to 20 uM incubated for 36 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
7.	ALA5039980	B	Protac activity at VHL/EGFR in human NCI-H1299 cells assessed as induction of EGFR degradation at 4 uM incubated for 6 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
8.	ALA5039981	B	Protac activity at VHL/PARP-1 in human NCI-H1299 cells assessed as induction of PARP degradation at 4 uM incubated for 6 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
9.	ALA5039982	B	Protac activity at VHL/EGFR in human NCI-H1299 cells assessed as decrease in EGFR degradation at up to 15 uM pretreated with proteasome inhibitor MG132 for 4 hr followed by incubation with compound for 6 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
10.	ALA5039983	B	Protac activity at VHL/PARP-1 in human NCI-H1299 cells assessed as decrease of PARP-1 degradation at up to 15 uM pretreated with proteasome inhibitor MG132 for 4 hr followed by incubation with compound for 6 hrs by Western blot analysis	Homo sapiens	1	ALA5038593	cell-based format	Scientific Literature
11.	ALA5039984	F	Antiproliferative activity against human NCI-H1299 cells assessed as inhibition of cell growth incubated for 72 hrs by CCK8 assay	Homo sapiens	3	ALA5038593	cell-based format	Scientific Literature
12.	ALA5039985	B	Binding affinity to recombinant human His/GST tagged EFGR (668 to 1220 residues) expressed in baculovirus infected cells assessed as dissociation constant incubated for 30 mins by microscale thermophoresis analysis	Homo sapiens	3	ALA5038593	cell-based format	Scientific Literature
13.	ALA5039986	B	Binding affinity to human GST-tagged PARP-1 ART domain (788 to 1014 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constant incubated for 30 mins by microscale thermophoresis analysis	Homo sapiens	3	ALA5038593	assay format	Scientific Literature