# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA5043811 | B | Inhibition of GST-tagged DCN1 (unknown origin) using AcUBE2M1-21 incubated for 30 mins by HTRF assay | Homo sapiens | 62 | ALA5042502 | single protein format | Scientific Literature | |
2. | ALA5043815 | B | Binding affinity to DCN1 (unknown origin) assessed as change in entropy by MM-PBSA method | Homo sapiens | 3 | ALA5042502 | single protein format | Scientific Literature | |
3. | ALA5043816 | B | Binding affinity to DCN1 (unknown origin) assessed as Gibbs free energy change by MM-PBSA method | Homo sapiens | 3 | ALA5042502 | single protein format | Scientific Literature | |
4. | ALA5043846 | F | Antifibrotic effect in SD rat cardiac fibroblast assessed as reduction in Ang II-induced collagen I upregulation preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis (Rvb = 71 %) | Rattus norvegicus | 2 | ALA5042502 | cell-based format | Scientific Literature | |
5. | ALA5043847 | F | Antifibrotic effect in SD rat cardiac fibroblast assessed as reduction in Ang II-induced activation of Nrf2 signaling pathway preincubated for 2 hrs followed by Ang II-stimulation and further incubated for 24 hrs by western blot analysis (Rvb = 43 %) | Rattus norvegicus | 2 | ALA5042502 | cell-based format | Scientific Literature |