# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3610426 | Functional | Positive inotropic effect in Sprague-Dawley rat ventricular myocytes assessed as change in ventricular cell contractility at 10 uM by video edge detector relative to control | Rattus norvegicus | 23 | ALA3608211 | cell-based format | Scientific Literature | |
2. | ALA3610427 | Functional | Positive inotropic effect in Sprague-Dawley rat ventricular myocytes assessed as change in ventricular cell contractility at 50 uM by video edge detector relative to control | Rattus norvegicus | 23 | ALA3608211 | cell-based format | Scientific Literature | |
3. | ALA3610430 | Binding | Activation of cardiac myosin S1 ATPase in bovine sarcomere at 10 uM by spectrophometric analysis in presence of actin thin filament complex relative to control | Bos taurus | 9 | ALA3608211 | assay format | Scientific Literature | |
4. | ALA3610432 | Binding | Activation of skeletal myosin S1 ATPase in rabbit psoas muscle at 10 uM in presence of actin thin filament complex | Oryctolagus cuniculus | 6 | ALA3608211 | tissue-based format | Scientific Literature | |
5. | ALA3610433 | Binding | Activation of smooth myosin S1 ATPase in chicken gizzard at 10 uM in presence of actin thin filament complex | Gallus gallus | 6 | ALA3608211 | assay format | Scientific Literature | |
6. | ALA851081 | ADME | Therapeutic Index measured as the ratio of CyD50(polio) / ED99(polio) values | Human enterovirus C | 38 | ALA1125251 | organism-based format | Scientific Literature | |
7. | ALA851082 | ADME | Therapeutic Index measured as the ratio of CyD50 (rhino) / ED99 (rhino) values. | 18 | ALA1125251 | assay format | Scientific Literature | ||
8. | ALA769455 | ADME | Cytotoxic dose at which 50% growth of normal cells is inhibited | Chlorocebus sabaeus | 47 | ALA1125251 | cell-based format | Scientific Literature | |
9. | ALA768385 | Functional | Minimum drug concentration at which 99% of the polio virus is inhibited | Human enterovirus C | 39 | ALA1125251 | organism-based format | Scientific Literature | |
10. | ALA768389 | Functional | Maximal non-toxic dose (MNTD) that shows antiviral activity. | Human enterovirus C | 61 | ALA1125251 | organism-based format | Scientific Literature | |
11. | ALA766871 | Functional | The ratio of the poliovirus viral titer of the virus control (reduction factor) to the viral titer in the presence of the maximal non-toxic dose (RF MNTD) | Human enterovirus C | 48 | ALA1125251 | organism-based format | Scientific Literature | |
12. | ALA766876 | Functional | Minimal dose which produces titer reduction at 10 ug/mL (mD RF10e3) | Human enterovirus C | 35 | ALA1125251 | organism-based format | Scientific Literature | |
13. | ALA882153 | Functional | Cytotoxic dose at which 50% growth of normal cells is inhibited against rhino virus infection. | Human rhinovirus sp. | 28 | ALA1125251 | organism-based format | Scientific Literature | |
14. | ALA799318 | Functional | Minimum drug concentration at which 99% of the rhino virus is inhibited. | Human rhinovirus sp. | 23 | ALA1125251 | organism-based format | Scientific Literature |